鼻咽癌与环境关系的探讨

利用土壤微量元素数据（１９７２９４４个），地形地貌数据（４５０２个），岩石类型数据（１０９２个），气象要素数据（６３６１０８０个），探讨鼻咽癌死亡率与人群生存的地质环境（土壤微量元素、地形地貌、岩石类型）和气象环境（年平均气温、年平均温差、年平均相对温度）的相关性。结果表明，土壤中Ｃｒ、Ｓｎ、Ｐｂ、Ｃｏ、Ｂｅ、Ｍｎ、Ｃｕ、Ｖ、Ｎｉ、Ｔｉ与鼻咽癌死亡率有相关性，等级相关系数ｒ分别为－０．４０９２（Ｐ＜０．０００５），０．４４２９（Ｐ＜０．０００５），０．３６５４（Ｐ＜０．０００５），－０．４５４６（Ｐ＜０．０００５），０．３４３９（Ｐ＜０．０００５），－０．２９２２（Ｐ＜０．００５），０．２８７４（Ｐ＜０．０１），－０．２６２０（Ｐ＜０．０２５），－０．２６６６（Ｐ＜０．０２５），－０．２４５８（Ｐ＜０．０２５），并有较明显的剂量—效应关系；山区与鼻咽癌死亡率的ｒ＝０．２５９３（Ｐ＜０．０１），岩浆岩、碎屑岩与鼻咽癌死亡率的ｒ分别为０．３９９４（Ｐ＜０．０００５），０．２２９４（Ｐ＜０．０２５），年平均气温、年平均温差、年平均相对湿度与鼻咽癌死亡率的ｒ分别为０．４１７６（Ｐ＜０．０００５），－０．４８１９（Ｐ

Relationship between the Nasopharyngeal Carcinoma and the Environment

The relationship between the mortality of nasopharyngeal carcinoma(NPC) and the geological and meteorological environment in the areas people grouping were analyzed with the data of trace elements in soil (1972944 data),the topographical geomorphic(4502 data),the types of rock(1092 data),the essential meteorological factors(6361080 data), combining the information of 1977 cases died of the nasopharyngeal carcinoma The results showed that the mortality of nasophoryngeal carcinoma was correlated to Cr,Sn,Pb,Co,Be,Mn,Cu,V,Ni,Ti in Soil,and the correlation coefficients of gradation( r ) were -0 409 2( P<0 000 5),0 442 9(P<0 000 5),0 365 4(P<0 000 5),-0 454 6(P<0 000 5),0 343 9(P<0 000 5),-0 292 2(P<0 005), -0 287 4(P<0 01),-0 262 0(P<0 025),-0 266 6(P<0 025),-0 245 8(P<0 025) respectively. It revealed a remarkable content effect relation.The r of the NPC mortality to mountainous areas was 0 259 3( P<0 01 );and 0 399 4( P<0 000 5),0 229 4(P<0 025 ) respectively to magmatic rock,clastic rock,and 0 417 6( P<0 000 5),-0 481 9(P<0 000 5),0 263 7(P<0 01 ) respectively to annual mean air temperature, annual mean temperature difference, annual mean relative humidity. The NPC mortality was positively correlated to the comprehensive influence coefficient of geology and meteorology, r=0 41(P<0 000 5 ), and revealed a remarkable content effect relation.