| 茵陈等六种中药对肝葡萄糖醛酸转移酶的体外诱导作用 |
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| 引用本文： | 刘义,龙盛京,谢云峰.茵陈等六种中药对肝葡萄糖醛酸转移酶的体外诱导作用[J].广西科学,1994,1(4):57-58. |
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| 作者姓名： | 刘义 龙盛京 谢云峰 |
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| 作者单位： | 广西医科大学, 南宁市滨湖路6号 530021,广西医科大学, 南宁市滨湖路6号 530021,广西医科大学, 南宁市滨湖路6号 530021 |
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| 摘 要： | 为了解中药治疗新生儿黄疸是否通过酶的诱导作用,用洋地黄皂甙作为体外肝葡萄糖醛酸转移酶(UGT)诱导的阳性对照物。用Black法测定茵陈(Artemisia capillaris)、黄连(Coptis chinensis)、大黄(Rheum officinale)、黄芩(Scutellaria baicalensis)、栀子(Fructus gardeniae)及甘草(Glycyrrhiza glabra)的水提物对Wistar大鼠肝匀浆在体外UGT酶诱导作用。结果表明,在体外实验,这6种中药水提取物不能增加大鼠肝细胞中UGT的活性。
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| 关 键 词： | 中医药疗法 黄疸 肝 体外诱导 UGT 茵陈 |
| 收稿时间： | 1984/8/9 0:00:00 |
Effects of Artemisia capillaris and Other Five Chinese Medicinal Herbs on the Activity of Rat Liver UDP-glucuronyltransferase |
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| Liu Yi,Long Shengjin and Xie Yunfeng.Effects of Artemisia capillaris and Other Five Chinese Medicinal Herbs on the Activity of Rat Liver UDP-glucuronyltransferase[J].Guangxi Sciences,1994,1(4):57-58. |
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| Authors: | Liu Yi Long Shengjin and Xie Yunfeng |
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| Institution: | Guangxi Medical University, 6 Binhu Road, Nanning, Guangxi, 530021,Guangxi Medical University, 6 Binhu Road, Nanning, Guangxi, 530021 and Guangxi Medical University, 6 Binhu Road, Nanning, Guangxi, 530021 |
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| Abstract: | For making sure that the treatment of neonatal jaundice with Chinese medicinal herbs is whether by induction of enzyme, the induction of Wistar rat liver uridinediphosphate glucuronyltransferase (UDP-GT) in vitro with the water extractives of six Chinese medicinal herbs,Artemisia capllaris,Coptis chinensis, Fructus srardeniae, Rheum officinale,Scutellaria baicalensis and Glycyrrhiza glabra were measureed by Black''s method. Digitonin was used as a positive enzyme-induced agent. The results showed that there were no difference between these herbs and blank control. |
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| Keywords: | glucuronyltransferase Chinese medicinal herb water extractive animal experiment neonatal jaudice |
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