激光拉曼光谱技术在生物活体研究中的应用进展

激光拉曼光谱技术能够实现物质的分子级探测并给出具有高度特异性的“指纹图谱”，具有快速、无创、灵敏度高等优势，在生物医学研究尤其是生物活体研究领域展现出良好的应用潜力，是当前的研究热点之一。生物活体研究能够在不影响生物机体正常生理环境的情况下获取最真实的反馈信息，具有无创性，是生物医学研究最理想的手段。本文从生物组织、血液这两个方面来阐述激光拉曼光谱技术在生物活体研究中的现状及进展，并对其未来的发展前景进行展望。

The Application Progress of Laser Raman Spectroscopy in the Study of Organisms in Vivo

Laser Raman spectroscopy can realize the molecular detection of substances and give a highly specific "fingerprint" spectrum.The optical detection technology has the advantages of rapid,non-invasive and high sensitivity,which has shown a good application potential in biomedical research,especially in the field of organisms in vivo. It is one of the current research hotspots.The biological research in vivo can obtain the most real feedback information without affecting the normal physiological environment of the organism.It is non-invasion and the most ideal means of biomedical research.In this paper,the status and progress of laser Raman spectroscopy technology in the study of organisms in vivo are expounded from two aspects of biological tissues and blood,and the prospect of its future development is prospected.