| NgR在中菊头蝠(Rhinolophus affinis)脑中分布 |
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| 引用本文： | 姚静,鲁亚平.NgR在中菊头蝠(Rhinolophus affinis)脑中分布[J].安徽师范大学学报(自然科学版),2009,32(1). |
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| 作者姓名： | 姚静 鲁亚平 |
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| 作者单位： | 安徽师范大学,生命科学学院,安徽,芜湖,241000;安徽师范大学,生命科学学院,安徽,芜湖,241000 |
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| 基金项目： | 国家自然科学基金，安徽省教委自然科学基金，NSF of Anhui Provincial Laboratory of the Conservation and Exploitation of Biological Resources，NSF of Anhui Key Laboratory of Biotic Environment and Ecologica Ecological Security，The Open Foundation of the Key Laboratory of Molecular Evolution and Biodiversity of Anhui Normal University |
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| 摘 要： | Nogo和其受体相互作用可能在抑制神经再生中发挥着重要作用.运用免疫细胞化学方法,本研究观察了Nogo受体(NgR)在中菊头蝠脑中的分布.结果显示NgR在中菊头蝠脑皮层各层均有表达.在海马,NgR主要分布在CA1、CA3和DG区的神经细胞胞膜、胞质或/和突起上.杏仁核、丘脑、室旁核、视上核、视交叉上核等也有NgR阳性神经细胞着色.在脑的白质,轴突着色明显.小脑的分子层、Purkinje细胞层和颗粒细胞层均有NgR免疫阳性反应,其中阳性反应的颗粒细胞最多.这些提示NgR可能介导其配基对中菊头蝠脑多个区域的神经细胞起作用.
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| 关 键 词： | Nogo Nogo受体 免疫细胞反应 脑 中菊头蝠 |
Distribution of NgR in the Brain of Rhinolophus affinis |
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| YAO Jing,LU Ya-ping.Distribution of NgR in the Brain of Rhinolophus affinis[J].Journal of Anhui Normal University(Natural Science Edition),2009,32(1). |
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| Authors: | YAO Jing LU Ya-ping |
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| Institution: | YAO Jing,LU Ya-ping(College of Life Sciences,Anhui Normal University,Wuhu 241000,China) |
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| Abstract: | An interaction of Nogo with NgR has been suggested to play an important role in limiting axonal growth.By means of immunocytochemistry,the present study investigated the distribution of NgR in the brain of Rhinolophus affinis. The results showed that the NgR protein appeared to be present in all layers of the brain neocortex.In the hippocampus,NgR immunoreactivity was widely located in neurons,mainly concentrated in CA1,CA3 of the stratum pyramidale and dentate gyrus.Neurons in the amygdala,thalamus,paraven... |
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| Keywords: | Nogo Nogo NgR immunoreactivity brain Rhinolophus affinis |
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