| 2-O-(庚氧基-2-羟丙基)-β-环糊精的制备及其包埋性能 |
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| 引用本文： | 郭艳玲,王宝琦,崔昭山,姜川.2-O-(庚氧基-2-羟丙基)-β-环糊精的制备及其包埋性能[J].天津科技大学学报,2012(1):27-30. |
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| 作者姓名： | 郭艳玲 王宝琦 崔昭山 姜川 |
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| 作者单位： | 天津科技大学理学院;天津科技大学材料科学与化学工程学院 |
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| 基金项目： | 天津市生物医学材料重点实验室开放课题基金资助项目(2011-1116-1) |
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| 摘 要： | 为了改善β–环糊精的包埋效果和保护能力,以正庚基缩水甘油醚和β–环糊精为原料,在1.5%的氢氧化钠碱性介质中反应,合成单取代烷基缩水甘油醚β–环糊精,并用FTIR、1H NMR、TGA进行了结构表征.分别用β–环糊精和2–O–(庚氧基–2–羟丙基)–β–环糊精对辣椒红色素进行包埋,结果表明:2–O–(庚氧基–2–羟丙基)–β–环糊精的包埋率比β–环糊精的多1倍,保护能力也得到有效提高.
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| 关 键 词： | 缩水甘油醚 β–环糊精衍生物 辣椒红色素 包埋率 |
Synthesis of 2-(heptyloxy-2-hydroxypropyl)-β-cyclodextrin and Its Embedding Properties |
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| GUO Yanling,WANG Baoqi,CUI Zhaoshan,JIANG Chuan.Synthesis of 2-(heptyloxy-2-hydroxypropyl)-β-cyclodextrin and Its Embedding Properties[J].Journal of Tianjin University of Science & Technology,2012(1):27-30. |
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| Authors: | GUO Yanling WANG Baoqi CUI Zhaoshan JIANG Chuan |
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| Institution: | 1.College of Science,Tianjin University of Science & Technology,Tianjin 300457,China;2.College of Material Science and Chemical Engineering,Tianjin University of Science & Technology,Tianjin 300457,China) |
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| Abstract: | For improving the embedding effect and protection ability of β-cyclodextrin,2-(heptyloxy-2-hydroxypropyl)-βcyclodextrin was synthesized in a 1.5% of sodium hydroxide solution using heptyl glycidyl ether and β-cyclodextrin as raw materials.The product’s structures were proved by the FTIR,1H NMR and TGA.The paprika oleoresin was embedded with β-cyclodextrin and substituted β-cyclodextrin,and the embedding ratio and stability of the two complexes were contrasted.The results show that the embedding ratio of β-cyclodextrin derivate is two times as many as β-cyclodextrin and its protection ability has also been improved effectively. |
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| Keywords: | glycidyl ether β-cyclodextrin derivate paprika oleoresin embedding ratio |
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