| 抗Gleevec(STI-571)耐受的Bcr-Abl蛋白酪氨酸激酶抑制剂研究进展 |
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| 引用本文： | 王立升,于海侠,郭鑫,肖军海,李松.抗Gleevec(STI-571)耐受的Bcr-Abl蛋白酪氨酸激酶抑制剂研究进展[J].广西大学学报(自然科学版),2006,31(1):10-14,48. |
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| 作者姓名： | 王立升 于海侠 郭鑫 肖军海 李松 |
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| 作者单位： | 1. 广西大学,化学化工学院,广西,南宁,530004
2. 军事医学科学院,毒物药物研究所,北京,100850 |
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| 摘 要： | 综述了抗G leevec(ST I-571)耐受的B cr-A b l蛋白酪氨酸激酶抑制剂的研究进展,主要介绍了PD 166326,BM S-354825,AM N 107和ON 012380四种酪氨酸激酶抑制剂.
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| 关 键 词： | Gleevec(STI-571) Bcr-Abl蛋白酪氨酸激酶 抑制剂 |
| 文章编号： | 1001-7445（2006）01-0010-05 |
| 收稿时间： | 2005-11-10 |
| 修稿时间： | 2005-11-102006-01-16 |
Research development of inhibitors against gleevec (STI-571)-resistant Bcr-Abl protien tyrosine kinase |
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| WANG Li-sheng,YU Hai-xia,GUO Xin,XIAO Jun-hai,LI Song.Research development of inhibitors against gleevec (STI-571)-resistant Bcr-Abl protien tyrosine kinase[J].Journal of Guangxi University(Natural Science Edition),2006,31(1):10-14,48. |
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| Authors: | WANG Li-sheng YU Hai-xia GUO Xin XIAO Jun-hai LI Song |
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| Institution: | 1. College of Chemistry and Chemical Engineering, Guangxi University,Guangxi 530004,China ; 2, Institute of Pharmacology and Toxicology, Academy of Military Medical Sciences,Beijing 100850,China |
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| Abstract: | On research development of inhibitors against Gleevec(STI-571)resistan Bcr-Abl protien tyrosine kinase,four inhibitors BMS354825,AMN107,ON012380 and PD166326 were reviewed in this article. |
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| Keywords: | review Gleevec(STI-571) Bcr-Abl protien tyrosine kinase inhibitors |
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