| 中枢记忆性T细胞和效应记忆性T细胞 |
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| 引用本文： | 徐林,熊思东.中枢记忆性T细胞和效应记忆性T细胞[J].科技导报(北京),2006,24(12):20-22. |
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| 作者姓名： | 徐林 熊思东 |
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| 作者单位： | 复旦大学免疫生物研究所 上海医学院免疫学系，复旦大学免疫生物研究所，上海医学院免疫学系，上海200032，上海200032 |
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| 基金项目： | 上海市卫生局领军人才计划资助项目(LJ06011) |
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| 摘 要： | 免疫记忆是适应性免疫应答的重要特征,其细胞学基础的阐明是疫苗开发和疾病预防的关键。近年来的研究表明,记忆性T细胞可以被进一步划分为中枢记忆性T细胞和外周记忆性T细胞2个亚群,它们的分布和功能迥异,在生物学特性上也不尽相同。二者关系的深入探讨对于免疫记忆的认识和疾病防治均具有重大的理论和实践意义。
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| 关 键 词： | 免疫记忆 记忆性T细胞 免疫分子 |
| 文章编号： | 1000-7857（2006）12-0020-03 |
| 收稿时间： | 2006-08-18 |
| 修稿时间： | 2006-08-18 |
Central Memory T Cells and Effector Memory T Cells |
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| XU Lin,XIONG Si-dong.Central Memory T Cells and Effector Memory T Cells[J].Science & Technology Review,2006,24(12):20-22. |
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| Authors: | XU Lin XIONG Si-dong |
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| Institution: | Institute for Immunobiology and Department of Immunology, Fudan University, Shanghai 200032, China |
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| Abstract: | Immunological memory is an important characteristic of adaptive immune response and elucidation of its cellular basis is critical for vaccine exploration and disease prevention. Recent studies have shown that memory T cells could be divided into central memory T cells and effector memory T cells, which were different in distribution, function and biological characteristics. Further investigations on their relationship may contribute to our understanding of immunological memory and the clinical therapy of tumor. |
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| Keywords: | immunological memory memory T cells immune molecules |
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