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《中医药-中药材重金属限量》ISO国际标准下中药材重金属污染现状与分析
引用本文:郭兰萍,周利,王升,康传志,郝庆秀,杨婉珍,周良云,李振浩,马忠华,黄璐琦.《中医药-中药材重金属限量》ISO国际标准下中药材重金属污染现状与分析[J].科技导报(北京),2017,35(11):91-98.
作者姓名:郭兰萍  周利  王升  康传志  郝庆秀  杨婉珍  周良云  李振浩  马忠华  黄璐琦
作者单位:1. 中国中医科学院中药资源中心;道地药材国家重点实验室培育基地, 北京 100700;
2. 广东药科大学中药学院, 广州 510006;
3. 中国中医科学院中药资源中心;无限极中草药品质研究联合实验室, 北京 100700;
4. 浙江寿仙谷珍稀植物药研究院, 武义 321200;
5. 无限极 (中国) 有限公司, 广州 510180
基金项目:药品医疗器械审评审批制度改革项目(ZG2016-1);中国中医科学院“十三五”重点领域研究专项(ZZ10-27);国家重点研发计划项目(2016YFF0202802);中药标准化项目(ZYBZH-C-HLJ-17,ZYBZH-C-GD-07)
摘    要: 本研究通过文献的收集并整理了中药材中重金属铅、砷、镉、汞的含量数据,以《中医药-中药材重金属限量》ISO国际标准为依据,分析了中药材中4种重金属元素的污染情况。结果显示,4种重金属的超标率分别为3.46%、4.03%、2.91%、1.41%。4种重金属均为动物类超标最高,另外,花、叶、全草所含重金属超标率较高;根和根茎类、茎木类次之,重金属超标率最小的为果实和种子类。分析发现目前各国家和地区的重金属限量标准主要根据植物类药材设定,还未有针对动物类药材制定的重金属限量标准,因此建议加快对动物类中药材重金属的研究及标准制定工作。

关 键 词:中药材  重金属  国际标准  统计分析  
收稿时间:2017-05-05

Statistic analysis of heavy metal residues in Chinese crude drugs with the international standards of Chinese Medicine-Chinese Herbal Medicine Heavy Metal Limit
GUO Lanping,ZHOU Li,WANG Sheng,KANG Chuanzhi,HAO Qingxiu,YANG Wanzhen,ZHOU Liangyun,LI Zhenhao,MA Zhonghua,HUANG Luqi.Statistic analysis of heavy metal residues in Chinese crude drugs with the international standards of Chinese Medicine-Chinese Herbal Medicine Heavy Metal Limit[J].Science & Technology Review,2017,35(11):91-98.
Authors:GUO Lanping  ZHOU Li  WANG Sheng  KANG Chuanzhi  HAO Qingxiu  YANG Wanzhen  ZHOU Liangyun  LI Zhenhao  MA Zhonghua  HUANG Luqi
Abstract:Through collection and analysis of relevant literature,the contents of heavy metals lead,arsenic,cadmium and mercury in Chinese herbal medicine are statistically analyzed under the ISO international standard of “Chinese medicine-Chinese herbal medicine heavy metal”.It is shown that the four kinds of heavy metals have excess rates of 3.46%,4.03%,2.91% and 1.41%,respectively,being the highest excessive ones in animal species.In addition,flowers,leaves,and whole grass have relatively higher contents of heavy metals,and they are followed by root and rhizome,stems and trees,while fruit and seed classes have the minimum exceeding rates for heavy metals.At present,the limits of heavy metals in various countries and regions are mainly based on plant medicinal materials,and there is no unique limit to heavy metals in animal medicines.Therefore,it is necessary to speed up the research and standard development of heavy metals in animal medicines.
Keywords:Chinese crude drugs  heavy metals  international standards  statistical analysis  
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