非均匀介质下的可调光流控器件及其生化应用

 探讨了非均匀介质下不同光流控器件及其生化应用。在微流控芯片上，主要从2个方面开发和实现各类具有光波导、透镜、细胞计数、化学检测等功能的新器件。首先，在液液非均匀介质下，通过调节沟道内液体流速，控制液体间的对流扩散来实现液体在微腔内的渐变折射率分布和阶跃分布，从而得到其特殊的光学特性，例如光束分离、弯曲、自聚焦等。其次，在固体非均匀介质下，利用特殊的微流结构与液体相结合，实现更加灵敏可调的新型探测手段。这些新型技术手段分别在生物传感、能源生产、细胞探测及海水检测等诸多应用中可发挥关键性作用。

Tunable optofluidic devices based on the inhomogeneous media and their biochemical applications

Different optofluidic devices and their biochemical applications in inhomogeneous media are discussed. In optofluidic chips, various new technologies, such as the optofluidic waveguides, the lenses, the cell counting and the chemical detection, are developed and implemented from two aspects. Firstly, in the liquid-liquid inhomogeneous medium, the gradient and step refractive index distributions of the liquid in the micro cavity are realized by adjusting the flow rates in the channel and controlling the convection-diffusion between the liquids to achieve the special optical properties, such as the beam separation, the bending, and the self-focusing. Secondly, in the solidliquid inhomogeneous medium, a series of adjustable and more sensitive detections are achieved by combining the special microfluidic structure with the liquids. These new technologies play a key role in many biochemical applications, for example, the biosensing, the energy production and the seawater detection. Thus, with the development of the optofluidics, the tunable devices in inhomogeneous media will have great potential biomedical applications.