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弯曲动脉血管中血液流动对血栓形成的影响
引用本文:刘赵淼,马瑞艳,叶红玲,张谭.弯曲动脉血管中血液流动对血栓形成的影响[J].科技导报(北京),2009,27(1).
作者姓名:刘赵淼  马瑞艳  叶红玲  张谭
作者单位:北京工业大学机械工程与应用电子技术学院,北京,100124  
基金项目:国家自然科学基金,北京市人事局留学回国人员择优资助项目,教育部留学回国人员科研启动基金 
摘    要:血栓性疾病大多发生在弯曲和血管分叉的位置附近,其形成机制和原因比较复杂,目前的研究主要集中在临床病例的治疗护理方面.临床观测表明,动脉疾病的发病机制和病变发展与血流动力学特征(如流场分布、壁面剪应力等)密切相关.采用计算流体力学方法,从血流动力学角度研究了弯曲血管中血液流动的改变对血管栓塞形成的影响.主要从血流入口初始速度、弯曲曲率半径、血管管径及血液黏度方面研究血液流动对血栓形成的影响.同时结合相关医学病例.从多学科角度分析并验证医学研究中有关血管弯曲对血栓形成机理的猜测.

关 键 词:弯曲血管  动脉血栓  壁面剪应力  壁面压强

Influence on Thrombosis of Blood Flow in Curved Blood Vessel
LIU Zhaomiao,MA Ruiyan,YE Hongling,ZHANG TanCollege of Mechanical Engineering , Applied Electronics Technology,Beijing University of Technology,Beijing ,China.Influence on Thrombosis of Blood Flow in Curved Blood Vessel[J].Science & Technology Review,2009,27(1).
Authors:LIU Zhaomiao  MA Ruiyan  YE Hongling  ZHANG TanCollege of Mechanical Engineering  Applied Electronics Technology  Beijing University of Technology  Beijing  China
Institution:LIU Zhaomiao,MA Ruiyan,YE Hongling,ZHANG TanCollege of Mechanical Engineering , Applied Electronics Technology,Beijing University of Technology,Beijing 100124,China
Abstract:Thrombus mostly occurs at the position near vessel bifurcation and sinuousness,whose formation mechanisms are relatively complicated and not clearly understood.Most investigations are now focused on the treatment and nursing of clinical cases and vitro experiments of medical thrombolysis.Clinical observations indicate that the formation mechanisms and pathological development of artery diseases have a close relationship with blood kinetics characteristics (such as distribution of flow field,wall shear stres...
Keywords:curved blood vessel  artery thrombus  wall shear stress  wall pressure  
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