| 基于聚吡咯的基因电子学:电化学DNA生物传感器 |
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| 引用本文： | 蒋稼欢,姜东成,李远,王静,SUNG K.L.Paul.基于聚吡咯的基因电子学:电化学DNA生物传感器[J].科技导报(北京),2009,27(11). |
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| 作者姓名： | 蒋稼欢 姜东成 李远 王静 SUNG K.L.Paul |
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| 作者单位： | 蒋稼欢,姜东成,李远,王静,JIANG Jiahuan,JIANG Dongcheng,LI Yuan,WANG Jing(重庆大学生物工程学院生物流变科学与技术教育部重点实验室,重庆,400044);SUNG K.L.Paul,SUNG K.L.Paul(重庆大学生物工程学院生物流变科学与技术教育部重点实验室,重庆400044;加利福尼亚大学圣地亚哥分校生物工程与整形外科系,圣地亚哥92093-0412,美国)
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| 基金项目： | 科技部国际科技合作重点项目，国家自然科学基金面上项目，重庆市自然科学基金面上项目，高等学校学科创新引智计划(111计划)项目 |
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| 摘 要： | 导电聚吡咯因其特殊结构和优异物化性能,成为构建电化学DNA生物传感器的一种新的介导材料,同时为未来基因电子学的发展提供了新的思路.综述了近年来聚吡咯在电化学DNA生物传感器中的实际应用,讨论了聚吡略电化学DNA生物传感器构建中的电极选择、电极修饰及DNA探针固定化策略;结合微阵列、微流控技术及纳米材料,对聚吡咯电化学DNA生物传感器的研究动向和应用做了探讨性展望.
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| 关 键 词： | 聚吡咯 电化学DNA传感器 微流控技术 微阵列技术 |
Polypyrrole-based Genolelectronics: Electrochemical DNA Biosensors |
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| JIANG Jiahuan,JIANG Dongcheng,LI Yuan,WANG Jing,SUNG K. L. Paul, . Key Laboratory of Education Ministry in Biorheological Science , Technology,Ministry of Education,Bioengineering College of Chongqing University,Chongqing ,China.Polypyrrole-based Genolelectronics: Electrochemical DNA Biosensors[J].Science & Technology Review,2009,27(11). |
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| Authors: | JIANG Jiahuan JIANG Dongcheng LI Yuan WANG Jing SUNG K L Paul Key Laboratory of Education Ministry in Biorheological Science Technology Ministry of Education Bioengineering College of Chongqing University Chongqing China |
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| Institution: | JIANG Jiahuan1,JIANG Dongcheng1,LI Yuan1,WANG Jing1,SUNG K. L. Paul1,2 1. Key Laboratory of Education Ministry in Biorheological Science , Technology,Ministry of Education,Bioengineering College of Chongqing University,Chongqing 400044,China 2. Department of Bioengineering , Orthopedic Surgery,University of California,San Diego,CA 92093-0412,USA |
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| Abstract: | Due to its special structure and excellent physical and chemical properties, the conducting polypyrrole is becoming a new material for fabricating electrochemical DNA biosensors and provides a new direction in the development of genolelectronics in future. The paper reviews the practical applications of polypyrrole in electrochemical DNA biosensors during recent years, discusses the selection and modification of electrodes and immobility strategies of DNA probe in the fabrication of the polypyrrole-based el... |
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| Keywords: | polypyrrole electrochemical DNA biosensor microfluidic microarray |
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