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| 应用于肿瘤磁感应热疗技术的磷酸钙磁性骨水泥介质的研究 | |
| 引用本文： | 王晓文,胡妍文,李利亚,崔瑞瑞,潘琳,郭静,魏兰镔,何柳,谢柳倩,唐劲天.应用于肿瘤磁感应热疗技术的磷酸钙磁性骨水泥介质的研究[J].科技导报(北京),2014,32(30):40-44. |
| 作者姓名： | 王晓文 胡妍文 李利亚 崔瑞瑞 潘琳 郭静 魏兰镔 何柳 谢柳倩 唐劲天 |
| 作者单位： | 1. 清华大学玉泉医院脑神经疾病研究所, 北京100049; 2. 北京中医药大学中药学院, 北京100102; 3. 中日友好医院中医肿瘤科, 北京100029; 4. 中日友好医院临床医学研究所, 北京100029; 5. 清华大学工程物理系;粒子技术与辐射成像教育部重点实验室, 北京100084 |
| 基金项目： | 国家自然科学基金项目(80171885,10775085) |
| 摘 要： | 磁性骨水泥是一种能兼顾骨修复和肿瘤热疗的新型磁感应热疗介质.为了获得性能优良的磁性骨水泥,本研究选择7 种微米级金属介质,分别对其形貌、升温能力、磁学性能进行筛选,筛选出性能优良的磁性介质.优选出的磁性介质与磷酸钙骨水泥按照不同比例混合,制备出不同配比的磁性骨水泥.通过测试凝固时间、抗压强度、体外升温等指标,进一步确定了磁性骨水泥的最优配比,为其应用提供了实验依据. |
| 关 键 词： | 磁感应热疗 骨肿瘤 骨水泥 |
| 收稿时间： | 2014-08-13 |
Novel Magnetic Bone Cement for Tumor Magnetic Hyperthermia |
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| WANG Xiaowen,HU Yanwen,LI Liya,CUI Ruirui,PAN Lin,GUO Jing,WEI Lanbin,HE Liu,XIE Liuqian,TANG Jintian.Novel Magnetic Bone Cement for Tumor Magnetic Hyperthermia[J].Science & Technology Review,2014,32(30):40-44. | |
| Authors: | WANG Xiaowen HU Yanwen LI Liya CUI Ruirui PAN Lin GUO Jing WEI Lanbin HE Liu XIE Liuqian TANG Jintian |
| Abstract: | Magnetic bone cement is a novel magnetic medium that generates heat under alternating fileds for bone tumor treatment as well as recovery of bone fracture. Seven kinds of metal microspheres were chosen to test their heat-generating abilities and magnetic properties. The selected materials were then mixed with calcium phosphate bone cements (CPC) at different powder liquid ratios. The setting time, mechanical tests, magnetic properties, and heat-generating abilities of the cement were analyzed. The results showed that the novel CPC-based magnetic bone cement had satisfactory heat-generating ability, which could be further applied for magnetic hyperthermia clinically. |
| Keywords: | magnetic hyperthermia bone tumor bone cement |
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