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蛇毒的研究进展及其在医药领域的应用
引用本文:王艳妮,鲍毅新.蛇毒的研究进展及其在医药领域的应用[J].浙江师范大学学报(自然科学版),2012,35(2):189-194.
作者姓名:王艳妮  鲍毅新
作者单位:浙江师范大学生态研究所,浙江金华,321004
基金项目:浙江师范大学博士科研启动基金资助项目(ZC304010086)
摘    要:就国内外主要毒蛇的蛇毒组分、对凝血系统的影响及蛇毒在医药领域的应用进行了综述.蛇毒的化学成分十分复杂,主要包括酶、神经毒性多肽、神经生长因子、膜活性多肽及其他生物活性肽,其中酶类包含多种与凝血系统、纤溶系统相关的成分.蛇毒在医药领域具有非常重要的作用,主要有促凝作用、溶栓作用、镇痛作用、降压作用和抗肿瘤作用.

关 键 词:蛇毒  活性肽  凝血系统  镇痛作用  抗肿瘤作用

Research progress on snake venom composition and its medical applications
WANG Yanni , BAO Yixin.Research progress on snake venom composition and its medical applications[J].Journal of Zhejiang Normal University Natural Sciences,2012,35(2):189-194.
Authors:WANG Yanni  BAO Yixin
Institution:(Institute of Ecology,Zhejiang Normal University,Jinhua Zhejiang 321004,China)
Abstract:It was overviewed the composition of snake venom,the effects of snake venom fractions on blood coagulation system,and the medical applications.The chemical composition of snake venom is very complex,containing the enzymes,neurotoxic polypeptide,nerve growth factor,active membranous peptides and other biologically active peptides.The enzymes contain a variety of components which are closely related with coagulation system and fibrinolytic system.The component of venom has a very important role in the medical fields,such as procoagulant effect,thrombolytic effect,analgesic effect,antihypertensive effect and antineoplastic effect.
Keywords:snake venom  active peptides  blood coagulation system  analgesic effect  antineoplastic effect
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