大豆磷脂对大鼠实验性高脂血症的预防

研究了大豆磷脂的降血脂作用，大鼠在食用高脂饲料的同时灌服大豆磷脂0.75g.kg^-1.d^-1-3.00g.kg^-1.d^-1,并于实验前，实验15d和21d时分别测血清总胆固醇（TC),甘油三酯（TG），高密度脂蛋白－胆固醇（HDL－C），低密度脂蛋白－胆固醇（LDL－C）的浓度，结果表明，大鼠在食用高脂饲料的同时，灌服大豆磷脂3.00g.kg^-1.d^-115d时，血清HDL－C浓度显著升高（P＜0．05），LDL－C浓度显著降低（P＜0．05）；21d时，0.75g.kg^-1.d^-1-3.00g.kg^-1.d^-1大豆磷脂均能使血清TC浓度降低（P＜0．05）,降幅28．8％－49．6％，说明大豆磷脂对大鼠实验性高脂血症有预防作用。

Prevention of soybean phospholipid from experimental hyperlipemia

The effect of soybean phosphatides on serum lipid reduction was studied. While fed a hyperlipid diet, rats were simultaneously force-fed soybean phosphatides(0.75 g·kg-1·d-1 ～3.00 g·kg-1·d-1 ) ang measured their levels of serum total cholesterol(TC),triglyceride(TG),high-d.lipoprotein-cholesterol(HDL-C)and low-d.lipoprotein-cholesterol (LDL-C)prior to the experiment,on d 15 and 21 of the experiment.A hyperlipid diet with simultaneous force-feeding of soybean phosphatides(3.00 g·kg-1·d-1)to rats yielded a significant increase of serum HDL-C level(P＜0.05) and a significant decrease of LDL-C level (P＜0.05) on d 15.On d 21 a dosage of 0.75 g·kg-1·d-1 ～3.00 g·kg-1·d-1 and yielded also a fall of serum TC level (P＜0.05),ranging from 28.8% to 49.6%.All of these results observed showed that soybean phosphatides have preventive effect on experimental hyperlipemic rats.