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集成非线性统计形状先验的M-S图像分割模型
引用本文:刘国才,肖茂发,段宣初,余志浩,阳维力,吴海燕.集成非线性统计形状先验的M-S图像分割模型[J].湖南大学学报(自然科学版),2012,39(2):47-53.
作者姓名:刘国才  肖茂发  段宣初  余志浩  阳维力  吴海燕
作者单位:湖南大学电气与信息工程学院;中南大学湘雅二医院
基金项目:国家自然科学基金资助项目(60872130,60835004,61072121);湖南省自然科学基金重点资助项目(09JJ3118);中央高校基本科研业务费
摘    要:为克服噪声污染、血管遮挡、光照不均匀、对比度小、个体间差异大等视网膜和视神经细微组织结构医学图像分割中固有的困难,提出了一种集成非线性形状先验的医学图像分割新方法.该方法首先采用非线性的核函数将目标先验形状窄带水平集映射到其核空间,然后在核空间进行主成分分析(PCA),以获取目标形状窄带水平集核空间的基底向量,并据此将目标形状先验知识集成到Mumford-Shah向量值图像分割模型,实现医学图像的分割.不同青光眼病人的视乳头图像分割实验结果表明,该方法能够有效地分割噪声大、对比度小且部分被血管遮挡的各阶段的青光眼病人视乳头图像.

关 键 词:核主成分分析(KPCA)  Mumford-Shah模型  统计形状先验知识  水平集方法  医学图像分割

M-S Model with Nonlinear Statistical Shape Prior for Image Segmentation
LIU Guo-cai,XIAO Mao-f,DUAN Xuan-chu,YU Zhi-hao,YANG Wei-li,WU Hai-yan.M-S Model with Nonlinear Statistical Shape Prior for Image Segmentation[J].Journal of Hunan University(Naturnal Science),2012,39(2):47-53.
Authors:LIU Guo-cai  XIAO Mao-f  DUAN Xuan-chu  YU Zhi-hao  YANG Wei-li  WU Hai-yan
Institution:1(1.College of Electrical and Information Engineering,Hunan Univ,Changsha,Hunan 410082,China; 2.The 2nd Xiangya Hospital,Central South Univ,Changsha,Hunan 410011,China)
Abstract:A modified Mumford-Shah model with nonlinear statistical shape prior was proposed to segment the optic nerve head in fundus images of poor quality,very low contrast,obscurity due to blood vessels,and distinct inter-differences of individuals.Firstly,the narrow band level set of shape prior was mapped into its kernel space by a nonlinear kernel function.Then,principal component analysis(PCA) was performed in the kernel space so as to acquire its base vectors,and statistical shape prior was integrated into a Mumford-Shah model.The segmentation results of the color optic nerve head images of patients in different stages of glaucoma have showed that the proposed model is effective and practicable.
Keywords:Kernel Principal Component Analysis(KPCA)  Mumford-Shah model  statistical shape prior  level set method  medical image segmentation
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