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复杂脑网络研究:现状与挑战
引用本文:张方风,郑志刚.复杂脑网络研究:现状与挑战[J].上海理工大学学报,2012,34(2):138-153.
作者姓名:张方风  郑志刚
作者单位:1. 北京物资学院 信息学院,北京 101149;北京师范大学 物理系,北京 100875
2. 北京师范大学 物理系,北京,100875
基金项目:国家自然科学基金,教育部博士点基金,北京师范大学自主科研基金创新群体资助项目,北京市优秀人才培养资助项目,北京物资学院青年科研基金
摘    要:以大脑网络研究为例,详细介绍了大脑网络的构建、结构网络、功能网络以及结构与功能的联系等方面的研究进展.基于复杂网络理论,对大脑结构网络和功能网络的分析得到很多重要的拓扑性质,如"小世界"、"无标度"、模块化以及核心脑区的分布等;另外发现认知功能、神经精神疾病与大脑结构和功能网络的拓扑结构变化或异常有关;总结了国内外在此领域的研究成果,提出了大脑网络研究工作面临的挑战,并展望了将来发展方向.

关 键 词:复杂网络  大脑网络  功能连接  结构连接  小世界  无标度

Complex Brain Networks:Progresses and Challenges
ZHANG Fang feng and ZHENG Zhi gang.Complex Brain Networks:Progresses and Challenges[J].Journal of University of Shanghai For Science and Technology,2012,34(2):138-153.
Authors:ZHANG Fang feng and ZHENG Zhi gang
Institution:1.School of Information,Beijing Wuzi University,Beijing 101149,China; 2.Department of Physics,Beijing Normal University,Beijing 100875,China)
Abstract:Progresses in studies of complex networks and its applications in brain network were retrospected,including the research on topology structure features of anatomical and functional brain networks,as well as on the relationship between brain structures and functions.Based on complex networks theory,some important topology features of anatomical and functional brain networks were reported,such as small world,scale free,modular and hub regions;then some new findings were presented about the relationship between cognitive function and neuropsychiatry disorder with abnormalities in functional connectivity and changes in topological structure changes.Several challenges and key issues that should be addressed in the future were further raised.
Keywords:complex networks  brain networks  functional connectivity  anatomical connectivity  small world  scale free
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