可降解下腔静脉滤器的生物力学性能及有限元分析

利用有限元分析和径向支撑力测试，分析不同支撑杆数目对新型生物可降解下腔静脉滤器（inferior vena cava filters， IVCF）的生物力学性能的影响。应用三维建模软件建立支撑杆数目为8， 10， 12的IVCF模型；通过室温拉伸左旋聚乳酸得到其应力-应变曲线，使用Abaqus软件模拟分析3种支架在压握和自扩张过程中的生物力学性能；同时将3种IVCF进行径向支撑力测试。结果表明，3种支架的应力峰值不同，但应力分布趋势相同；其径向支撑力随支撑杆数目的增加而减小，自扩张性能则与之相反；10杆IVCF表现出较好的综合力学性能，经压握后不仅有足够的径向支撑力，而且可以实现自我扩张，对血管壁的损伤最小。

Biomechanical Properties and Finite Element Analysis of the Biodegradable Inferior Vena Cava Filter

The effects of support pole numbers on biomechanical properties of a novel biodegradable inferior vena cava filter (IVCF) were investigated by finite element analysis and radial force tests. The IVCF model with 8, 10 and 12 supporting poles were established by three-dimensional modeling software. The stress-strain curve of poly L-lactide fibers was obtained by tensile test at room temperature. The biomechanical properties of the three stents under crimp and expansion condition were then simulated and analyzed by using the Abaqus software. Meanwhile, the three IVCFs were subjected to radial support force test. The results show that the three stents shows different peak stresses with similar trend of stress distribution. The radial support force decreases with the increase in the supporting pole numbers. However, the self-expansion performance shows the opposite trends. The 10 pole IVCF performs the superior comprehensive mechanical property, which includes sufficient radial force after crimp, achievement of self-expansion, and the least damage to vessel wall.