局部照射对大鼠睾丸性激素、白细胞的影响

为了解不同剂量局部照射对大鼠睾丸重量、超微结构及性激素、白细胞的影响，对大鼠不同剂量局部照射后，睾丸组织称重，超微结构观察，测定血清睾酮、促卵泡激素水平，白细胞计数。结果表明，睾丸组织重量随照射剂量增中及时间延长。逐渐减轻，并与照射剂量及时间呈正相关；但当照剂量增加，照射时间延长至一定程度后，睾丸重量基本不变，出现相 期，超微结构观察可见生精细胞变性、坏死、随时间延长呈不可逆性变化，间质细胞形态结

The Influence of Local Irradiation on Testis, Sexual Hormones and Leukocyte

In order to investigate the influence of different dosages of local irradiation on weight of testis, ultrastructure, sexual hormones and leukocyte. The different dosages of local irradiation were performed on testis of Wistar rats. The weignt of testis, serum level of testosterone, follicle Stimulating hormone and Leukocyte count were measured and ultrastructure was observed. The results showed that the weight of testis decreased gradually as dosages of irradiation increased and time of irradiation was prolonged. There was a positive correlation between the weight of testis and dosage and time of irradiation. But the weight of testis was not altered significantly when the increase of dosage and time of irradiation to a certain extent. Observation of ultrastructure showed the degeneration and necrosis of spermospore, and these changes were irreversible as time of irradiation lasted longer. Morphosis of interstitial cells was not altered significantly and totally recovered, testosteroe, follicle stimulating hormone and leukocyte count had no remarkable changes during the whole experimental processes. These results indicated that local irradiation of testis might damage its function of speramatogenesis, but had no influence on secretion of sexual hormones and leukocyte.