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大小鼠主要病毒血清抗体检测结果与分析
引用本文:魏巍,刘霄磊,刘家森,郭东春,姜骞,林欢,司昌德,曲连东.大小鼠主要病毒血清抗体检测结果与分析[J].实验动物科学,2011,28(6):23-25.
作者姓名:魏巍  刘霄磊  刘家森  郭东春  姜骞  林欢  司昌德  曲连东
作者单位:中国农业科学院哈尔滨兽医研究所实验动物中心,黑龙江省实验动物质量监督检验站,哈尔滨150001
摘    要:目的评估清洁级大鼠、小鼠的微生物学质量。方法参照国家标准GB/T 14926-2001,依据单纯随机抽样原则从相关单位生产繁殖群采集样品,检测主要病毒血清抗体水平。结果检测31只大鼠,其中仙台病毒(SV)和汉坦病毒(HV)抗体阳性率均为0;检测280只小鼠,其中25只小鼠肝炎病毒(MHV)抗体阳性,10只小鼠仙台病毒(SV)抗体阳性,1只小鼠鼠痘病毒(Ect)抗体阳性。结论清洁级小鼠的病毒监测工作及质量控制需加强。

关 键 词:实验动物  血清抗体  大鼠  小鼠

The Detection and Analysis of Serum Antibody for Main Virus in Rats and Mice
WEI Wei , LIU Xiao-lei , LIU Jia-sen , GUO Dong-chun , JIANG Qian , LIN Huan , SI Chang-de , QU Lian-dong.The Detection and Analysis of Serum Antibody for Main Virus in Rats and Mice[J].Shiyan Dongwu Kexue,2011,28(6):23-25.
Authors:WEI Wei  LIU Xiao-lei  LIU Jia-sen  GUO Dong-chun  JIANG Qian  LIN Huan  SI Chang-de  QU Lian-dong
Institution:WEI Wei,LIU Xiao-lei,LIU Jia-sen,GUO Dong-chun,JIANG Qian,LIN Huan,SI Chang-de,QU Lian-dong(Laboratory Animal Center of Harbin Veterinary Research Institute,Heilongjiang Provincial Quality Monitoring Center for Laboratory Animals,Harbin 150001,China)
Abstract:Objective To evaluate the microbiological quality of clean rat and mouse.Methods According to the national standard GB/T 14926-2001,we collected samples from producing and breeding group in some related farms with a principle of simple random sampling,and detected the serum antibody level of main virus.Results The number of Sendai virus(SV) and hanta virus(HV) antibody positive were negative in 31 rats;and the number of positive mouse hepatitis virus(MHV) antibodies is 25,and Sendai virus(SV) 10,Ectromelia(...
Keywords:laboratory animals  serum antibody  rat  mouse  
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