| 制作线栓法大鼠脑缺血再灌注模型的要点及体会 |
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| 引用本文： | 何芳雁,韩春妮,李艳,林青.制作线栓法大鼠脑缺血再灌注模型的要点及体会[J].实验动物科学,2013,30(4):46-48. |
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| 作者姓名： | 何芳雁 韩春妮 李艳 林青 |
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| 作者单位： | 云南中医学院药理教研室,昆明,650500 |
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| 基金项目： | 国家自然科学基金项目(项目编号：81160514),云南省科技计划项目(项目编号：2010CG022) |
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| 摘 要： | 摘要: 线栓法复制大鼠脑缺血再灌注损伤模型具有无需开颅、缺血时间可控、梗塞部位较明确等优点，被国内外学
者广泛用于脑缺血再灌注损伤的研究。我们对常用的线栓法大鼠脑缺血再灌注损伤模型进行了比较研究，本文介
绍我们对复制该模型的要点及体会。
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| 关 键 词： | 线栓法 脑缺血再灌注模型 |
The Essentials and Experience of Developing Model of Cerebral Ischemia-reperfusion by Suture-occluded Method in Rat |
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| HE Fang-yan
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HAN Chun-ni
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LI Yan
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LIN Qing.The Essentials and Experience of Developing Model of Cerebral Ischemia-reperfusion by Suture-occluded Method in Rat[J].Shiyan Dongwu Kexue,2013,30(4):46-48. |
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| Authors: | HE Fang-yan HAN Chun-ni LI Yan LIN Qing |
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| Institution: | HE Fang-yan;HAN Chun-ni;LI Yan;LIN Qing;Department of Pharmacology,Yunnan University of TCM; |
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| Abstract: | The method of developing model of cerebral ischemia-reperfusion in the rats by suture-occlude method had the advantages of no need for craniotomy,controllable duration of ischemia,and more definitive infarct location.At present the method has been extensively used in China and abroad for studying ischemia-reperfusion injury.A comparative study on developing model of cerebral ischemia-reperfusion in the rats by suture-occlude method has been carried out in our laboratory.This paper presented the essentials and experience of developing model of cerebral ischemia-reperfusion by suture-occluded method in the rat. |
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| Keywords: | suture method cerebral ischemia-reperfusion model |
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