| 实验兔的使用次数对热原敏感性的影响 |
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| 引用本文： | 李守申,杨春宏.实验兔的使用次数对热原敏感性的影响[J].实验动物科学,2004,21(4):19-21. |
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| 作者姓名： | 李守申 杨春宏 |
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| 作者单位： | 山东鲁抗医药股份有限公司质监中心,济宁,272121 |
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| 摘 要： | 目的 探讨实验兔的使用次数对热原敏感性产生的影响。方法 用不同使用次数的实验兔进行试验，对同一实验兔注射统一规定剂量的细菌内毒素，然后每间隔30min测量实验兔体温一次，共8次。结果 随着实验兔使用次数的增加，其体温升高幅度逐渐降低。结论 实验兔在多次使用后对热原的敏感性降低。
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| 关 键 词： | 实验兔 热原 细菌内毒素 敏感性 |
| 文章编号： | 1006-6179(2004)04-0019-03 |
| 修稿时间： | 2004年2月16日 |
The Effect of Repeat use of Experiment Rabbit on Sensitivity of Pyrogen |
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| LI Shou-shen,YANG Chun-hong.The Effect of Repeat use of Experiment Rabbit on Sensitivity of Pyrogen[J].Shiyan Dongwu Kexue,2004,21(4):19-21. |
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| Authors: | LI Shou-shen YANG Chun-hong |
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| Abstract: | Objective\ To study the effect of repeat use of experiment rabbit and the sensitivity of pyrogen.Method The rabbits were used for different times, but the same does of endotoxin were injected each rabbit, and then the temperature at every 30 minutes within four hours after injection were recorded. Results When the rabbits were reused in the pyrogen fest, the temperature of the rabbits become lower. Conclusion Rabbit's sensitivity of pyrogen became lower after they were used for several times in pyrogen test. |
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| Keywords: | Experiment rabbit Pyrogen Bacterioendotoxin Sensitivity |
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