盐酸甲氯芬酯在急性脑出血中的临床应用疗效观察

目的观察盐酸甲氯芬酯治疗急性脑出血临床病例疗效。方法将62例脑出血患者进行随机均分治疗组和对照组。对照组用常规治疗方法，治疗组在常规治疗的基础上，加用盐酸甲氯芬酯0．5g，静脉滴注，每日1次，共4周。于治疗前及治疗后第4周后分别进行神经功能缺损评分及疗效评定。结果治疗4周后，治疗组神经功能缺损评为（9．6±6．3）分，明显低于对照组的（14．4±7．6）分（P〈0．05）；治疗组的显效率和有效率分别为61．29％和87．10％，显著高于对照组的38．71％和54．85％（P〈0．05）。结论盐酸甲氯芬酯可促进脑出血患者的神经功能保护和康复作用。

Meclofenoxate Hydrochloride in Patients with Acute Cerebral Hemorrhage in the Clinical Efficacy Observation

Objective To evaluate the efficacy of hydrochloric acid meclofenoxate on the treatment of acute cerebral hemorrhage.Methods Sixty- two cases were divided into treatment group and control group randomly. Necurological fimctional defieitscores were utilized for assessment before given treatment, on the 4 weeks after treatment, the patient was assessed again and the efficacy was recordsd. Results After 4 weeks treatment, the neurological functional deficit scores of treated group were 9.6 ± 6.3, whereas those of the control group were 14. 4 ± 7.6. There was significant difference between the two groups （ P 〈 0.05）. There were also significant differenceds between the two groups in terns of apparmt effect rote（treated group 61.29% ,control group 38.71% P 〈 0.05） and improvement rote （ treated group 87.10%, control group 54.85 % ; P 〈 0.05 ）. Conclusion Hydrochloric acid meclofenoxate can accelerate the recovery of neural function after cerebral hemorrhage.