| 脑肿瘤干细胞分子生物学研究进展 |
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| 引用本文： | 彭硕,龚熹,汪艳璐,罗玉萍,李思光. 脑肿瘤干细胞分子生物学研究进展[J]. 江西科学, 2011, 29(1): 55-58,78 |
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| 作者姓名： | 彭硕 龚熹 汪艳璐 罗玉萍 李思光 |
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| 作者单位： | 南昌大学生命科学与食品工程学院,江西,南昌,330031 |
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| 摘 要： | 脑肿瘤干细胞是脑肿瘤组织中存在的一小类具有无限增殖、自我更新和多向分化等干细胞特性的肿瘤细胞。肿瘤干细胞是肿瘤发生、发展、侵袭、转移、耐药、复发等恶性行为的主要根源,只有杀死脑肿瘤干细胞才能彻底治愈脑肿瘤。本文对当前脑肿瘤干细胞研究在分子生物学水平上取得的一些进展进行了综述。
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| 关 键 词： | 脑肿瘤 脑肿瘤干细胞 分子生物学 |
Progress in the Molecular Biology Study of Brain Tumor Stem Cells |
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| PENG Shuo,GONG Xi,WANG Yan-lu,LUO Yu-ping,LI Si-guang. Progress in the Molecular Biology Study of Brain Tumor Stem Cells[J]. Jiangxi Science, 2011, 29(1): 55-58,78 |
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| Authors: | PENG Shuo GONG Xi WANG Yan-lu LUO Yu-ping LI Si-guang |
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| Affiliation: | (School of Life Sciences and Food Engineering,Nanchang University,Jiangxi Nanchang 330031 PRC) |
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| Abstract: | Recent studies have confirmed that there is a small population of brain tumor cells with the abilities of stem cells,like extensive proliferation,self-renew and multi-directional differentiation,which called Brain tumor stem cells（BTSCs）.BTSCs contribute to tumor initiation,progression,invasion,metastasis,therapeutic resistance and relapse.Only by killing brain BTSCs can we thoroughly cure brain tumor.In this review,we discuss the recent progress in the molecular biology study of brain tumor stem cells. |
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| Keywords: | Brain Tumor Brain tumor stem cell Molecular biology |
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