| 乌枣健脑安神片的定性定量研究 |
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| 引用本文： | 徐彦,张志锋,吴春蕾,吴莉莉.乌枣健脑安神片的定性定量研究[J].西南民族学院学报(自然科学版),2009,35(6):1202-1206. |
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| 作者姓名： | 徐彦 张志锋 吴春蕾 吴莉莉 |
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| 作者单位： | 西南民族大学少数民族药物研究所,四川成都610041 |
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| 摘 要： | 目的对乌枣健脑安神片进行定性定量分析，为其质量标准的制定提供方法和依据．方法采用TLC法对处方中的制何首乌、补骨脂、酸枣仁、五味子等4味药材进行定性鉴别，采用HPLC法测定乌枣健脑安神片的君药制何首乌中2，3，5，4’-四羟基二苯乙烯-2-O-β-D．葡萄糖苷的含量．结果在TLC鉴别中能捡出制何首乌中的大黄素、大黄素甲醚，补骨脂中的补骨脂素、异补骨脂素，酸枣仁中的齐墩果酸以及五味子和五味子甲素，在HPLC测定中，进样量在0．0481～0．7669μg范围内有良好的线性关系，r=0．9999（n=8），平均回收率97．6％，RSD=1．4％（n=9）．结论该方法简便、准确、专属性强，重现性、回收率好，可作为控制乌枣健脑安神片质量的方法．
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| 关 键 词： | 乌枣健脑安神片 TLC 2 3 5 4'-四羟基二苯乙烯-2-O—β-D-葡萄糖苷 HPLC |
Qualitative and quantitative analysis on Wuzao Jiannao Anshen Tablets |
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| XU-Yan,ZHANG Zhi-feng,WU Chun-lei,WU Li-li.Qualitative and quantitative analysis on Wuzao Jiannao Anshen Tablets[J].Journal of Southwest Nationalities College(Natural Science Edition),2009,35(6):1202-1206. |
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| Authors: | XU-Yan ZHANG Zhi-feng WU Chun-lei WU Li-li |
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| Institution: | (Ethnic Pharmaceutical Institute of Southwest University for Nationalities, Chengdu 610041, P.R.C.) |
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| Abstract: | Objective： To establish the quality standard for Wuzao Jiannao Anshen Tablets. Methods ： Applying the technique of TLC, Radix Polygoni multiflori preparata, Psoralea corylifolia, Semen Ziziphi spinosae, and Fructus Schisandrae Chinensis are identified. The conternts of 2,3,5,4＇-tetrahydroxy-stilbene-2-O-β-D-glycoside are determined by HPLC. Results： Emodin and Physcione from Radix Polygoni multiflori preparata, Psoralen and isopsoralen from Psoralea corylifolia, Oleanic acid from Semen Ziziphi spinosae, Fructus Schisandrae Chinensis and Deoxyschizandrin can be qualified by TLC. 2,3,5,4＇- tetrahydroxy-stilbene-2-O-β-D-glycoside show a good linear relationship in the range of 0.0481-0.7669 μg μg and the average recovery is 97.6%, RSD=1.4 （n=9）. Conclusion： The methods are simple, accurate and effective. It may be used for quality control of Wuzao Jiannao Anshen Tablets. |
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| Keywords: | TLC 2 3 5 HPLC |
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