| 板蓝根粗提液抑制流感病毒的实验研究 |
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| 引用本文： | 胡兴昌,郑伟强.板蓝根粗提液抑制流感病毒的实验研究[J].上海师范大学学报(自然科学版),2003,32(1):62-65. |
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| 作者姓名： | 胡兴昌 郑伟强 |
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| 作者单位： | 上海师范大学,生命与环境学院,上海,200234 |
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| 基金项目： | 上海市教委自然科学发展基金(CL98015) |
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| 摘 要： | 对板蓝根凝聚粗提液的抗流感病毒作用进行了研究。用丙酮脱脂提取板蓝根生药的凝集素，并分别测定各样品的血凝活性，并用45.3mg/mL的样品对流感病毒（A1／京防／97－53H1N1，A1／京防／262／95）进行了体外抑制试验。结果表明：板蓝根凝集素对流感病毒具有显著的直接杀灭作用和预防作用及较好的治疗作用，而且得出抑制流感病毒的效果与板蓝根凝集素血凝活性的高低有关。
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| 关 键 词： | 板蓝根粗提液 流感病毒 血凝活性 |
| 文章编号： | 1000-5137(2003)01-0062-04 |
| 修稿时间： | 2002年1月9日 |
Resistance to Isatia indigotica Fort Lectin Inhibit Influenza Virus |
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| HU Xing-chang,ZHENG Wei-qiang.Resistance to Isatia indigotica Fort Lectin Inhibit Influenza Virus[J].Journal of Shanghai Normal University(Natural Sciences),2003,32(1):62-65. |
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| Authors: | HU Xing-chang ZHENG Wei-qiang |
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| Abstract: | The Isatia indigotica Fort lectin is a bioative nonimmune protein. The lectin extracted from Isatia indigotica Fort roots. The lectin' s hemagglutination activity was tested to estimate the role of inhibition on influence virus (A1/Jing Fang/97-53H1 N1 and A1/Jing Fang/262/95). The results showed that the lectin(45. 3mg/mL) had a function of remarkable killing, treatment and prevention influenza virus, and the hemagglutination activity of the lectin in different breeds had a remarkable difference in inhibition on influenza virus, and the hemagglutination activity of the lectin was in proportin to inhibition on influenza virus. |
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| Keywords: | Isatia indigotica Fort Lectin Influenza virus Hemaggiutination activity |
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