| 液质联用技术快速识别喜树叶提取物中的微量活性成分 |
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| 引用本文： | 尤珠双,徐晓燕,郭成,潘远江.液质联用技术快速识别喜树叶提取物中的微量活性成分[J].云南民族大学学报(自然科学版),2011,20(5). |
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| 作者姓名： | 尤珠双 徐晓燕 郭成 潘远江 |
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| 作者单位： | 1. 浙江大学化学系,浙江杭州,310027
2. 浙江海正药业股份有限公司,浙江台州,318000 |
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| 基金项目： | 国家自然科学基金(21025207;20975092) |
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| 摘 要： | 应用高效液相色谱/电喷雾串联质谱联用技术(HPLC/ESI-MSn)对药用植物喜树叶提取物中的微量活性成分进行分析研究,探讨了喜树叶中喜树碱类及鞣花酸类化合物的质谱裂解规律,建立了1种快速识别喜树中喜树碱类生物碱和鞣花酸类成分的液质联用方法;运用这一方法在线识别了5个喜树碱类生物碱和5个鞣花酸类成分,其中3个推测为新化合物.
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| 关 键 词： | 液质联用技术分析 喜树叶提取物 喜树碱 鞣花酸 |
Rapid Identification of Minor Active Constituents of Leaves of Camptotheca by HPLC/ESI-MS~n |
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| YOU Zhu-shuang,XU Xiao-yan,GUO Cheng,PAN Yuan-jiang.Rapid Identification of Minor Active Constituents of Leaves of Camptotheca by HPLC/ESI-MS~n[J].Journal of Yunnan Nationalities University:Natural Sciences Edition,2011,20(5). |
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| Authors: | YOU Zhu-shuang XU Xiao-yan GUO Cheng PAN Yuan-jiang |
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| Institution: | YOU Zhu-shuang1,XU Xiao-yan2,GUO Cheng1,PAN Yuan-jiang1(1.Department of Chemistry,Zhejiang University,Hangzhou 310027,China,2.Zhejiang Hisun Pharmaceutical Co.,Ltd.,Taizhou 318000,China) |
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| Abstract: | The minor active constituents of alkaloids and ellagic acids in leave extracts of Camptotheca were investigated by HPLC/ESI-MSn.In this study,the characteristic fragmentation patterns of camptothecin and ellagic acid were discussed,and a rapid and sensitive method was developed for the characterization and identification of alkaloids and ellagic acids in Camptotheca.With this method,5 alkaloids and 5 ellagic acids were rapidly identified,among which 3 are new compounds. |
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| Keywords: | HPLC/ESI-MS Camptotheca alkaloid ellagic acid |
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