| 龙血竭主要黄酮类成分及其DPPH自由基清除活性研究 |
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| 引用本文： | 王芳芳,胡琳,王兴红.龙血竭主要黄酮类成分及其DPPH自由基清除活性研究[J].云南民族大学学报(自然科学版),2015(3):189-193. |
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| 作者姓名： | 王芳芳 胡琳 王兴红 |
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| 作者单位： | 云南民族大学民族药资源化学国家民委-教育部重点实验室;云南大学微生物研究所 |
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| 基金项目： | 云南省自然科学基金(2012FB172) |
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| 摘 要： | 采用硅胶、Sephadex LH-20和反相RP C-18等柱色谱分离技术,从广西龙血竭甲醇提取物中分离了8个主要的黄酮类化合物,经综合波谱分析分别鉴定为:5,4'-二羟基-7-甲氧基-6-甲基黄烷(1),7,4'-二羟基高异黄烷(2),7,4'-二羟基-8-甲氧基高异黄烷(3),7,4'-二羟基高异黄酮(4),4'-羟基-2,4-二甲氧基二氢查尔酮(5),4,4'-二羟基-2-甲氧基二氢查尔酮(6),2,4,4'-三羟基-6-甲氧基二氢查尔酮(7),4,4'-二羟基-2,6-二甲氧基二氢查尔酮(8).还测定了化合物1~8的DPPH自由基清除活性,化合物1表现出较强活性.
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| 关 键 词： | 龙血竭 黄酮 化学成分 DPPH |
Main flavonoids in Chinese dragon's blood and their DPPH free radical scavenging activities |
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| WANG Fang-fang;HU Lin;WANG Xing-hong.Main flavonoids in Chinese dragon's blood and their DPPH free radical scavenging activities[J].Journal of Yunnan Nationalities University:Natural Sciences Edition,2015(3):189-193. |
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| Authors: | WANG Fang-fang;HU Lin;WANG Xing-hong |
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| Institution: | WANG Fang-fang;HU Lin;WANG Xing-hong;Key Laboratory of Chemistry in Ethnic Medicinal Resources,State Ethnic Affairs Commission and Ministry of Education of China,Yunnan Minzu University;Institute of Microbiology,Yunnan University; |
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| Abstract: | Chinese Dragon's blood is the red resin of Dracaena cochinchinensis( Lour.) S. C. Chen. This research has focused on the main flavonoids of Dragon's blood and their DPPH free radical scavenging activities. Eight compounds have been obtained from the methanolic extract of Dragon's blood by the column chromatography on Sigel,Sephadex LH-20 and RP C-18. Their structures have been identified by combined spectroscopic analyses as 5,4'-dihydroxy-7-methoxy-6-methylflavane( 1),7,4'-dihydroxyhomoisoflavane( 2),7,4'-dihydroxy-8-methoxyhomoisoflavane( 3),7-hydroxy-3-( 4-hydroxybenzyl)-chroman-4-one( 4),4'-hydroxy-2,4-dimethoxydih-ydrochalcone( 5),4,4'-Dihydroxy-2-methoxydihydrochalcone( 6),2,4,4'-trihydroxy-6-rnethoxydihydrochalcone( 7) and 4,4'-Dihydroxy-2,6-dimethoxydihydrochalcone( 8). Compounds 1—8 have been tested for their abilities to scavenge 1,1-diphenyl-2-picrylhydrazyl( DPPH) free radical. Compound 1 has displayed relatively strong activity. |
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| Keywords: | Dragon's blood flavonoids chemical constituents DPPH |
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