| 血清中43种滥用药物的固相萃取法研究 |
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| 引用本文： | 杨丽君,REITER A.血清中43种滥用药物的固相萃取法研究[J].云南大学学报(自然科学版),2003,25(5):434-437441. |
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| 作者姓名： | 杨丽君 REITER A |
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| 作者单位： | 1. 云南公安高等专科学校,禁毒系,云南,昆明,650223
2. 吕贝克医科大学法医研究所,德国,吕贝克,D-23562 |
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| 摘 要： | 使用CLEANSCREEN? 固相萃取柱分别对血清中43种滥用药物进行提取方法的研究,其提取物分别采用GC-MS和UV方法测定.结果表明:在43种滥用药物中,回收率超过90%的药物有26种,居80%～90%的药物有8种,居60%～80%的药物有另外8种,小于60%的药物仅有1种.因此CLEANSCREEN? 固相萃取柱可用于血清中该43种滥用药物的提取或筛选分析,且是一种快速、简便及具有较高回收率的提取方法.
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| 关 键 词： | 滥用药物 固相萃取法 CLEANSCREEN?固相萃取柱 回收率 |
| 文章编号： | 0258-7971(2003)05-0434-04 |
Studies on solid-phase extraction of 43 drugs abused in serum |
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| REITER A.Studies on solid-phase extraction of 43 drugs abused in serum[J].Journal of Yunnan University(Natural Sciences),2003,25(5):434-437441. |
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| Authors: | REITER A |
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| Institution: | 1. Department of Narcotics Control, Yunnan Public Security College, Kunming 650223, China;2. Institute of Legal Medicine of Medical University of Luebeck, Luebeck D-23562, Germany |
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| Abstract: | CLEAN SCREEN column was used for extraction of 43 abused drugs in serum. The comcentrations of the 43 drugs in the extacts were determined by CG-MS and/or UV.Among the 43 drugs,the recoveries of 26 drugs exceed 90%,the recoveries of 8 drugs were between 80% and 90%,the recoveries of 8 drugs were between 60% and 80% and the recovery of 1 drug was under 60%.Based on the results,CLEAN SCREEN column could be used for extraction or the 43 drugs in serum.The method was simple rapid and with a high recovery. |
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| Keywords: | drugs abused solid-phase extraction CLEAN SCREEN column recovery |
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