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藏药革叶兔耳草化学成分的研究
引用本文:刘娜,张娜,夏沙,赵雪秋,陈兴,杨丽娟.藏药革叶兔耳草化学成分的研究[J].云南大学学报(自然科学版),2015,37(2):272-278.
作者姓名:刘娜  张娜  夏沙  赵雪秋  陈兴  杨丽娟
作者单位:1. 云南民族大学 民族药资源化学国家民委-教育部重点实验室, 云南 昆明 650500;
2. 云南省高校民族地区资源清洁转化重点实验室, 云南 昆明 650500
基金项目:国家自然科学基金(21162042);云南省教育厅科学研究基金重大专项(ZD2014010);云南民族大学创新团队项目,民族药协同创新中心项目.
摘    要:对产于云南香格里拉的革叶兔耳草(Lagotis alutacea W.W.Smith)的化学成分进行研究.用硅胶柱层析对化合物进行分离,并用光谱方法进行结构鉴定.共分离鉴定了11个化合物:10-O-(3,4-dimethoxy-(E)-cinnamoyl)catalpol(1),10-O-(3,4-dimethoxy-(Z)-cinnamoyl)catalpol(2),ehrenoside(3),lagotoside(4),木犀草素(luteolin,5),木犀草素-4'-甲醚(luteolin-4'-methyl ether,6),木犀草素-7-O-β-D-葡萄糖苷(luteolin-7-O-β-D-glucoside,7),茴香酸(anisic acid,8),香草醛(vanillin,9),β-谷甾醇(β-sitosterol,10)和胡萝卜苷(daucosterol,11).以上化合物均为首次从该植物中分离得到.

关 键 词:革叶兔耳草  化学成分  环烯醚萜苷  苯丙素苷  黄酮

Study on the chemical constituents of Lagotis alutacea
LIU Na,ZHANG Na,XIA Sha,ZHAO Xue-qiu,CHEN Xing,YANG Li-juan.Study on the chemical constituents of Lagotis alutacea[J].Journal of Yunnan University(Natural Sciences),2015,37(2):272-278.
Authors:LIU Na  ZHANG Na  XIA Sha  ZHAO Xue-qiu  CHEN Xing  YANG Li-juan
Institution:1. Key Laboratory of Ethnic Medicine Resource Chemistry, State Ethnic Affairs Commission & Ministry of Education, Yunnan University of Nationalities, Kunming 650500, China;
2. Key Laboratory of Resource Clean Conversion in Ethnic Regions, Education Department of Yunnan, Kunming 650500, China
Abstract:The chemical constituents of Lagotis alutacea W.W.Smith collected in Shangri La were studied.The compounds were isolated by silica column chromatography, and the structures were elucidated by spectral methods.Eleven compounds were isolated and identified as 10-O-(3, 4-dimethoxy-(E)-cinnamoyl)catalpol (1), 10-O-(3, 4-dimethoxy-(Z)-cinnamoyl)catalpol (2), ehrenoside (3), lagotoside (4), luteolin (5), luteolin-4''-methyl ether (6), luteolin-7-O-β-D-glucoside (7), anisic acid (8), vanillin (9), β-sitosterol (10) and daucosterol (11) respectively.All the compounds were isolated from this plant for the first time.
Keywords:Lagotis alutacea W  W  Lagotis alutacea W" target="_blank">Smith'')" href="#">Lagotis alutacea W  W  Smith  chemical constituents  iridoid glycoside  phenypropanoid glycoside  flavonoid
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