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狮耳花的民族药物学研究进展
引用本文:王晓玲,袁绿益.狮耳花的民族药物学研究进展[J].西南民族大学学报(自然科学版),2016,42(5):484-491.
作者姓名:王晓玲  袁绿益
作者单位:西南民族大学 药学院,西南民族大学 药学院
基金项目:四川省科技厅科技支撑项目 (2015SZ0040)
摘    要:目的:综合报道狮耳花在植物学,药理学,植物化学,生物活性,毒理学及其商业方面的研究。方法:对1900年~2015年的文献进行广泛查阅,包括电子数据库Scopus,SciFinder, Pubmed, Google Scholar中的摘要,全文文章和相关书籍。 结果:狮耳花中主要含萜类化合物,尤其是半日花烷型二萜类。还有很多化学成分被认为并非来自狮耳花,比如,具有轻度神经兴奋性的益母草碱,从未出现在狮耳花提取物。结论:尽管对狮耳花的研究和应用已有很多报道,但是仍需要对该植物中的未知成分进行深入研究,尤其对有神经性作用的相关成分进行系统分离和鉴定,具有重要的学术价值.

关 键 词:狮耳花  半日花烷型二萜类  药理活性
收稿时间:2016/9/7 0:00:00
修稿时间:2016/9/14 0:00:00

Progress in pharmacieticul of Leonotis leonurus
WANG Xiao-ling and YUAN lv-yi.Progress in pharmacieticul of Leonotis leonurus[J].Journal of Southwest University for Nationalities(Natural Science Edition),2016,42(5):484-491.
Authors:WANG Xiao-ling and YUAN lv-yi
Institution:College of Pharmacy,Southwest University for Nationalities,Sichuan Chengdu 610041,P.R.C
Abstract:Objective: To summarize the botanical aspects, ethnopharmacology, phytochemistry, biological activity, toxicity and commercial aspects of L. leonurus. Methods: An extensive review of the literature from 1900 to 2015 was carried out. Electronic databases including Scopus, Sci Finder, Pubmed, Google Scholar were used as data sources. All abstracts, full-text articles and books written in English were considered. Result: L. leonurus contains mainly terpenoids, particularly labdane diterpenes. Other compounds reported by some authors have been isolated from the plant, including the mildly psychoactive alkaloid. Leonurine has however, never been reported in the extracts of L. leonurus. Conclusion: Despite the publication of various papers on L. leonurus, there is still demand for definitive research and clarification of other compounds. Research has proven the psychoactive effects of the crude extract of L. leonurus, but confirmation of the presence of psychoactive compounds, as well as isolation and characterization, is still required.
Keywords:Leonotis Leonurus  labdane diterpenes  pharmacological activities
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