水貂源大肠杆菌对9种抗菌药物敏感性试验

为了解水貂源大肠杆菌对抗菌药物的敏感性,指导兽医临床有效防治大肠杆菌病.采集山东省某水貂养殖场水貂粪便;采用常规的分离、鉴定方法获得8株大肠杆菌菌株;采用K-B纸片扩散法检测菌株对9种抗菌药物的药物敏感性.结果表明,菌株对9种药物呈不同水平的耐药性(耐药率范围25.0~100.0%),对妥布霉素、阿米卡星100%耐药;对粘杆菌素、氟喹诺酮类呈较低耐药率;62.5%的菌株对所检测的8种药物耐药.以上结果说明了本次检测的水貂源大肠杆菌耐药性非常严重,临床上应根据药敏试验结果,合理和谨慎地使用抗菌药物以控制水貂大肠杆菌病.

Drug sensitivity test of Escherichia coli isolates from minks to nine antimicrobial agents

This paper was to detect antibiotic susceptibility patterns of E.coli isolates from minks for preventing and curing colibacillosis effectively in veterinary clinic. Fece samples were collected from mink farm in Shandong province; Eight E.coli isolates were confirmed by routine methods; Susceptibilities to 9 antimicrobial agents were defined by K-B disk diffusion. The results showed that the isolates had different resistance levels to 9 agents (resistant rates ranged from 25.0% to 100.0%), 100% isolates were resistant to tobramycin and amikacin; Majority of the isolates showed relatively low resistance levels to bacillus polymyxa and FQS; 62.5% isolates were resistant to 8 agents tested. The conclusion is that the resistance of E.coli isoates from mink is very serious, and antimicrobial agents must be prudently selected by antimicrobial susceptibility test to control colibacillosis in mink.