微生物氮代谢调控研究进展

氮素是核酸及蛋白质的主要成分,也是构成生物体的必需元素,对微生物的生长发育、次生代谢以及信息交流等方面均有重要作用.为维持自身的生长发育,不同微生物进化出特有的代谢调控系统,以应对不断变化的氮素供应环境.目前所知的代谢调控方式主要有GlnR、Ntr、sRNA调控系统,但不同的调控系统之间区别甚大.该文综述了几种常见的氮代谢调控系统,以期为深入了解并运用微生物的氮代谢调控机制提供参考.

The Research Progress on the Regulation of Microbial Nitrogen Metabolism

Nitrogen is not only the main component of nucleic acid and protein,but also an essential element in the composition of organisms,which plays an important role in the growth and development of microorganisms,secondary metabolism and information exchange.In order to maintain their own growth and development,different microorganisms have evolved unique metabolic regulation systems to cope with the changing nitrogen supply environment.At present,the main known metabolic regulation systems are GlnR,Ntr and sRNA regulation systems,but there are great differences between different regulation systems.The several common nitrogen metabolism regulation systems are reviewed,in order to provide reference for in-depth understanding and application of microbial nitrogen metabolism regulation mechanism.