| 蝙蝠葛碱提多糖对Hela细胞增殖的影响 |
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| 引用本文： | 王志宏,薛建斌,姜文艳,张桂荣.蝙蝠葛碱提多糖对Hela细胞增殖的影响[J].东北师大学报(自然科学版),2011(4):132-136. |
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| 作者姓名： | 王志宏 薛建斌 姜文艳 张桂荣 |
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| 作者单位： | 长春中医药大学基础医学院;吉林大学生命科学学院; |
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| 基金项目： | 国家自然科学基金资助项目(30870251,31070309); 教育部985平台项目; 吉林省中医药管理局计划项目(2010-078) |
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| 摘 要： | 利用蝙蝠葛根提取多糖成分,并应用噻唑蓝还原法(MTT)检测了蝙蝠葛多糖对Hela细胞增殖的抑制作用及细胞毒性作用.结果表明:蝙蝠葛碱提多糖在质量浓度较低时,对Hela细胞的增殖有促进作用,此作用在质量浓度为0.25 mg/mL时达到最大,此时Hela细胞增殖率为149％.随着浓度的进一步加大,Hela细胞的生长逐渐受到...
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| 关 键 词： | 蝙蝠葛 多糖 癌症 |
A study on effects of Menispermum dauricum alkali polysaccharide on Hela cell proliferation |
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| WANG Zhi-hong,XUE Jian-bin,JIANG Wen-yan,ZHANG Gui-rong.A study on effects of Menispermum dauricum alkali polysaccharide on Hela cell proliferation[J].Journal of Northeast Normal University (Natural Science Edition),2011(4):132-136. |
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| Authors: | WANG Zhi-hong XUE Jian-bin JIANG Wen-yan ZHANG Gui-rong |
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| Institution: | WANG Zhi-hong1,XUE Jian-bin2,JIANG Wen-yan2,ZHANG Gui-rong2(1.Basic Medical College,Changchun University of Chinese Medicine,Changchun 130117,China,2.Life Science College,Jilin University,Changchun 130012,China) |
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| Abstract: | Alkaloids in Menispermum dauricum may inhibit tumour cell viability in virtro,and may lead to cell apoptosis.Yet,the inhibiting capability depends on its concentration and time.This experiment means to extract polysaccharides from the Menispermum dauricum roots and to measure the inhibiting effects of its alkali polysaccharide on Hela cell proliferation and cytotoxicity by MTT reduction method.The study indicates that Menispermum dauricum alkali polysaccharides may facilitate the Hela cell proliferation whe... |
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| Keywords: | Menispermum dauricum polysaccharide tumour |
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