| 基于混沌游戏图形表示的细菌必需基因与非必需基因的Hurst指数特征对比分析 |
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| 引用本文： | 周茜,孙逸飞,徐桂芝.基于混沌游戏图形表示的细菌必需基因与非必需基因的Hurst指数特征对比分析[J].北京理工大学学报,2015,35(S1):87-91. |
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| 作者姓名： | 周茜 孙逸飞 徐桂芝 |
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| 作者单位： | 1. 河北工业大学电磁场与电器可靠性省部共建重点实验室, 天津 300130;2. 河北工业大学电气工程学院, 天津 300130,1. 河北工业大学电磁场与电器可靠性省部共建重点实验室, 天津 300130;2. 河北工业大学电气工程学院, 天津 300130,1. 河北工业大学电磁场与电器可靠性省部共建重点实验室, 天津 300130;2. 河北工业大学电气工程学院, 天津 300130 |
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| 基金项目： | 河北省自然科学基金资助项目(F2012202016);国家自然科学基金资助项目(61305077);河北省高等学校创新团队领军人才培育计划资助项目(LJRC003) |
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| 摘 要： | 必需基因是维持生物体生命活动必不可少的基因,基因特征的选取对于必需基因的理论预测识别方法至关重要.作者采用分形理论对DEG必需基因数据库中的所有细菌物种进行了基于Hurst指数的必需基因与非必需基因特征对比分析,旨在提取必需基因区别于非必需基因的显著特征.结果表明,绝大部分必需基因与非必需基因序列具有长程相关性,所分析细菌物种的必需基因和非必需基因的Hurst指数均较好地遵从Gamma分布规律,且两类基因的Hurst指数具有显著性差异.
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| 关 键 词： | 混沌游戏图形表示 必需基因 基因特征 Hurst指数 |
| 收稿时间： | 2015/3/20 0:00:00 |
Hurst Exponent Comparative Analysis of Bacterial Essential and Non-Essential Genes Based on Chaos Game Representation |
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| ZHOU Qian,SUN Yi-fei and XU Gui-zhi.Hurst Exponent Comparative Analysis of Bacterial Essential and Non-Essential Genes Based on Chaos Game Representation[J].Journal of Beijing Institute of Technology(Natural Science Edition),2015,35(S1):87-91. |
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| Authors: | ZHOU Qian SUN Yi-fei and XU Gui-zhi |
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| Institution: | 1. Province-Ministry Joint Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability, Hebei University of Technology, Tianjin 300130, China;2. School of Electrical Engineering, Hebei University of Technology, Tianjin 300130, China,1. Province-Ministry Joint Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability, Hebei University of Technology, Tianjin 300130, China;2. School of Electrical Engineering, Hebei University of Technology, Tianjin 300130, China and 1. Province-Ministry Joint Key Laboratory of Electromagnetic Field and Electrical Apparatus Reliability, Hebei University of Technology, Tianjin 300130, China;2. School of Electrical Engineering, Hebei University of Technology, Tianjin 300130, China |
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| Abstract: | Essential genes are indispensable for the maintenance of life activity. Gene feature selecting is crucial for the theoretical predictions and recognition of essential genes. In this paper, based on chaos game representation method, comparative analysis of the Hurst exponent of the essential and non-essential genes of all bacterials in DEG essential genes database was made. The result shows that both essential and non-essential gene sequences have long range correlation. There is a linear relationship between Hurst exponent and gene sequences, and the Hurst exponents of essential and non-essential genes have significant difference. Therefore, Hurst exponent may be an effective feature for distinguishing essential and non-essential genes. The results provide theoretical basis for bacterial species essential genes prediction. |
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| Keywords: | chaos game representation essential genes gene feature Hurst exponent |
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