| 含银抗感染制剂的研究进展 |
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| 引用本文： | 张净宇,王卓鹏,郭嵩,金辉,王金成,于吉红.含银抗感染制剂的研究进展[J].科学通报,2010,55(17):1639-1647. |
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| 作者姓名： | 张净宇 王卓鹏 郭嵩 金辉 王金成 于吉红 |
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| 作者单位： | 吉林大学中日联谊医院骨科;吉林大学化学学院;无机合成与制备化学国家重点实验室; |
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| 基金项目： | 卫生部部署(管)医院临床学科重点项目(2007353); 国家重点基础研究发展计划(2007CB936402); 吉林大学研究生创新基金(20091014)资助 |
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| 摘 要： | 自古代起,银的抗菌性就已引起了人们的注意,并被广泛地应用在烧伤、创伤、细菌感染等的治疗上.近年来,随着细菌耐药性和各种变异病毒的产生,作为一种无机抗感染制剂,银更是受到了人们的广泛关注.本文主要介绍银应用于医学研究的状况,并对银离子、纳米银、以及各种负载银制剂,如以羟基磷灰石(HA)为载体的银制剂、以分子筛(zeolite)为载体的银制剂和以有机聚合物(PMMA)为载体的银制剂等的抗感染性研究进行了综述,为下一步临床研究奠定基础.
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| 关 键 词： | 银 抗感染性 纳米银 羟基磷灰石 分子筛 有机聚合物 |
| 收稿时间： | 2009-12-28 |
Progress in research on silver as an anti-infective agent for medical uses |
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| Zhang JingYu,Wang ZhuoPeng,Guo Song,Jin Hui,Wang JinCheng & Yu JiHong Orthopedic.Progress in research on silver as an anti-infective agent for medical uses[J].Chinese Science Bulletin,2010,55(17):1639-1647. |
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| Authors: | Zhang JingYu Wang ZhuoPeng Guo Song Jin Hui Wang JinCheng & Yu JiHong Orthopedic |
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| Institution: | Zhang JingYu1,Wang ZhuoPeng2,Guo Song2,Jin Hui1,Wang JinCheng1 & Yu JiHong2 1 Orthopedic Department,China-Japan Union Hospital of Jilin University,Changchun 130033,China,2 State Key Laboratory of Inorganic Synthesis and Preparative Chemistry,College of Chemistry,Jilin University,Changchun 130012 |
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| Abstract: | Silver has been in use since ancient times for the treatment of burns,wounds and some bacterial infections because of its antibacterial properties.Recently,with the increasing resistance of microorganisms and viruses to antibiotics and antivirals,silver as a broad-spectrum anti-infective agent is of increasing interest for medical uses.In this article,the applications of silver in medicine and recent progress in research on recently developed silver-incorporated anti-infective agents,such as silver-hydroxya... |
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| Keywords: | silver anti-infection silver nanoparticles hydroxyapatite zeolite polymer |
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