Evidence for an unusual multifunctional protoreceptor in hormone action |
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Authors: | M. K. Agarwal J. Paillard M. Philippe |
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Affiliation: | (1) INSERM and CNRS, F-75005 Paris, (France);(2) Present address: 15, rue de l'Ecole de Médecine, F-75270 Paris Cedex 06, France |
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Abstract: | Summary Contrary to the techniques of mere association, column chromatography has revealed a protoreceptor that accepts aldosterone agonists and antagonists only in the physiological target, the kidney, and is absent in non-targets, liver and serum; it is furthermore different from the aldosterone specific receptor in renal cytosol.Supported in part by grants from the CNRS AI 03 1917 and UER Broussais Hôtel Dieu. |
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