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Removal of 5-bromo-2-deoxyuridine incorporated in liver DNA of newborn and young adult rats
Authors:G. Arfellini  G. Prodi  S. Grilli
Affiliation:(1) Institute of Cancerology, University of Bologna, via S. Giacomo 14, 40126 Bologna, Italy
Abstract:
Summary 5-bromo-2-deoxyuridine (BUdR) removal from liver DNA in newborn and young adult rats has been demonstrated: it forms the basis of a reliable method to measure DNA repair in tissues provided with detectable DNA synthetic activity.This work was supported by a grant from Consiglio Nazionale delle Ricerche, Rome, and lsquoDonazione Testonrsquo, Bologna, Italy.
Keywords:
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