ST/HR斜率与单光子发射计算机断层摄影术心肌灌液显像

分析了ST/HR斜率对冠心病(CHD)的诊断价值,应用ST/HR斜率计算机自动分析系统与运动介入单光子发射型计算机断层摄影术(SPECT)心肌显像同时进行,检测60例临床怀疑CHD患者,并对30例健康正常人进行了ST/HR斜率检测。结果表明:ST/HR斜率与SPECT心肌显像二者结果有良好的相关性(r=0.58,P<0.005),符合率为80%,SPECT阳性者其斜率值高于SPECT阴性者及正常人群(均P<0.05);若以SPECT为标准,ST/HR斜率与普通运动试验诊断CHD的敏感性分别为81.6%和73.9%(P>0.05),特异性分别为77.3%和45.5%(P<0.05),以正常人为ST/HR斜率与普通运动试验的特异性分别为93.3%和70.0%(P<0.05);SPECT显示2个以上节段心肌缺血者,其斜率值明显高于单一节段缺血者(P<0.05)。

Value of ST/HR slope in detecting coronary artery disease

The diagnosis values of the ST-segment/heart rate(ST/HR) slope in detecting coronary heart disease (CHD) is assessed.. Computer assisted ST/HR slope analysis and exercise stress single photon emission computed tomography(SPECT) myocardial perfusion in aging were conducted at the same time in 60 patients which were suspected to suffer from CHD. Besides 30 normal subjects were examined by ST/HR slope method. The ST-segment/heart rate correlated well with myocardial imaging (r=0.58, P<0.005), the agreement rate was 80%. P<0.05 slope in group with positive SPECT was higher than that in group with negative results and normal subjects (all P<0.05) .When the SPECT results were used as the criteria for CHD, sensitivity and specificity of P<0.05 slope for the detecting of CHD were 81.6% and 77.3%,respecitively, those of standard exercise test ECG criteria were 73.9% and 45.5%, respecitively (specificity, P<0.05 Vs ST/HR slope).The specificity of ST/HR slope was higher as compared with standard exercise test ECG criteria (93.3%Vs 70.0%, P<0.05)in normal subjects. Moreover, the XT/HR slope in two or more segments ischemia patients was higher than that in single segments (P<0.05). These findings suggest that ST/HR slope is a good method for the diagnosis of CHD and it can detect the extent of myocardial ischemia tosome degree.