Unravelling the signal-transduction network in B lymphocytes |
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| Authors: | Sambrano Gilberto R Chandy Grischa Choi Sangdun Decamp Dianne Hsueh Robert Lin Keng-Mean Mock Dennis O'Rourke Nancy Roach Tamara Shu Hongjun Sinkovits Bob Verghese Mary Bourne Henry |
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| Institution: | Department of Cellular and Molecular Pharmacology, University of California, San Francisco, 513 Parnassus Avenue, San Francisco, California 94143, USA. sambrano@cmp.ucsf.edu |
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| Abstract: | The Alliance for Cellular Signaling has chosen the mouse B lymphocyte as a model system to understand basic principles that govern cellular signalling. Progress to that end has focused initially on establishing a reproducible experimental cell system and characterizing essential signalling responses. Although unravelling this complex network will take years, findings revealed in the interim will prove immensely useful to the scientific community at large. |
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