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Dax1 is required for testis determination |
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| Authors: | Meeks Joshua J Weiss Jeffrey Jameson J Larry |
| Affiliation: | Division of Endocrinology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois 60611, USA. |
| Abstract: | The orphan nuclear receptor, Dax1, was originally proposed to act as an 'anti-testis' factor. We find, however, that Nr0b1 (also called Dax1 and Ahch, which encodes Dax1) is in fact required for testis differentiation. |
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