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丽江紫乌头中的二萜生物碱
引用本文:龚元,李咏梅,赵静峰,羊晓东,李良.丽江紫乌头中的二萜生物碱[J].云南大学学报(自然科学版),2012,34(5):566-569.
作者姓名:龚元  李咏梅  赵静峰  羊晓东  李良
作者单位:黔南民族医学高等专科学校;云南大学教育部自然资源药物化学重点实验室
基金项目:国家重点基础研究发展计划资助项目(2009CB522300);云南省自然科学基金资助项目(2010GA014)
摘    要: 对丽江紫乌头中的二萜生物碱进行研究.利用反复硅胶柱层析,重结晶等分离手段从中分离鉴定了6个二萜生物碱:查斯曼宁(chasmanineⅠ),塔拉萨敏(talatizamine Ⅱ),草乌甲素(crassicauline A Ⅲ),丽江乌头碱(foresaconitine Ⅳ),acoforestinine(Ⅴ),滇乌碱(yunaconitine Ⅵ).其中化合物Ⅰ、Ⅲ、Ⅳ、Ⅴ为首次从该种植物中分离得到.

关 键 词:丽江紫乌头  二萜生物碱  乌头属

Diterpenoid alkaloids from Aconitum episcopale Levl.
GONG Yuan,LI Yong-mei,ZHAO Jing-feng,YANG Xiao-dong,LI Liang.Diterpenoid alkaloids from Aconitum episcopale Levl.[J].Journal of Yunnan University(Natural Sciences),2012,34(5):566-569.
Authors:GONG Yuan  LI Yong-mei  ZHAO Jing-feng  YANG Xiao-dong  LI Liang
Institution:1.Qiannan National Medicine College,Duyun 558000,China; 2.Key Laboratory of Medicinal Chemistry for Natural Resources,Ministry of Education,School of Chemical Science and Technology, Yunnan University,Kunming 650091,China)
Abstract:The diterpenoid alkaloids of Aconitum episcopale Levl. were studied and six diterpenoid alkaloids were isolated by silica column chromatography.The structures of theses compounds were elucidated as chasmanineⅠ,talatizamine Ⅱ,crassicauline A Ⅲ,foresaconitine Ⅳ,acoforestinine Ⅴ,yunaconitine Ⅵ by spectral methods.Compounds Ⅰ,Ⅲ,Ⅳ,Ⅴ were isolated from this plant for the first time.
Keywords:Aconitum episcopale Levl    diterpenoid alkaloid  Aconitum L
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