透明质酸对人工关节材料的润滑作用

配合人工软骨材料的研究，探讨透明质酸（ＨＡ）作为摩擦副的人工滑液时的润滑性能。在ＰＶＡ－Ｈ／３１６Ｌ，ＰＶＡ－Ｈ／ＰＶＡ－Ｈ两类摩擦副上，利用锥板式粘度计，改进后的振子式摩擦仪和Ｍ２０００型磨损试验机，测定了不同质量分数的ＨＡ溶液的流变性质、摩擦性能和磨损性能，结果表明，ＨＡ溶液一定程度上具有天然滑液的流变性质，并有效地降低了摩擦副的摩擦磨损，其对ＰＶＡ－Ｈ／ＰＶＡ－Ｈ摩擦副润滑作用更佳，且０．７

Lubricating Behaviour of Hyaluronic Acid in Artificial Articular Materials

Supporting the study of artificial articuar cartilage materials, the research and development of an artificial synovial fluid of Hyaluronic acid (HA) was carried out. With two lubricated sliding pairs, PVAH/316L and PVA-H/PVA-H, an modified oscillator-type tri-biometer and M-2000 wear test machine were used to detemine the rehological properties and lubricating behaviour of a series of HA solution.The experimental results showed that the solution of HA had the rehological properties similaring to the natural synovial fluid to a cehain eXtellt, and decreased the ffiction and wear of tWo kinds of lubricatCd sliding pairs, also it rendered abetter 1ubricating effection on PVA-unVA-H than on PVA-H/3 l6L. The sofution of HA with O.75% (massfraction) showed a better lubricating behaviour than 30% (volumic fraction) Bovine Serum. So HA solutionwould be a promising Anficial synovial fluid.