| 无损检测血液灌注率的常热流方法 |
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| 引用本文： | 李和杰,张学学,柯江华,刘静. 无损检测血液灌注率的常热流方法[J]. 清华大学学报(自然科学版), 2002, 42(10): 1354-1356 |
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| 作者姓名： | 李和杰 张学学 柯江华 刘静 |
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| 作者单位： | 清华大学,热能工程系,北京,100084;中国科学院,理化技术研究所低温中心,北京,100080 |
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| 基金项目： | 清华大学机械工程学院基础研究基金项目 |
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| 摘 要： | 建立了无损测量活体组织血液灌注率的皮肤表面常热流加热方法。基于 Pennes生物传热方程 ,得出体表温度响应与组织血液灌注率之间的计算关系式。研究了不同体表热流、血液灌注率下的组织温升 ,分析了体表接触热阻对估测血液灌注率的影响。该法中接触热阻的影响可通过在皮肤与热偶间采用高热导率油脂减少到可忽略的程度。该文方法与其他方法相比 ,简便易行精度高
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| 关 键 词： | 血液灌注率 无损测量 常热流加热 |
| 文章编号： | 1000-0054(2002)10-1354-03 |
| 修稿时间： | 2001-10-22 |
Non-invasive estimate of blood perfusion using the temperature response to a constant surface heat flux |
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| LI Hejie ,ZHANG Xuexue ,KE Jianghua ,LIU Jing. Non-invasive estimate of blood perfusion using the temperature response to a constant surface heat flux[J]. Journal of Tsinghua University(Science and Technology), 2002, 42(10): 1354-1356 |
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| Authors: | LI Hejie ZHANG Xuexue KE Jianghua LIU Jing |
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| Affiliation: | LI Hejie 1,ZHANG Xuexue 1,KE Jianghua 1,LIU Jing 2 |
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| Abstract: | A closed form analytical solution of the Pennes' bio heat equation was obtained for the temperature distribution in biological tissue subjected to constant surface heat flux. The surface temperature elevations were related to the blood perfusion and heating flux. The sensitivities of the temperature elevation to blood perfusion and heating flux were investigated. The influence of the thermal contact resistance on the perfusion estimate is relatively small and can be effectively eliminated by the application of highly conductive grease. This analysis provides a theoretical foundation for a new non invasive approach to blood perfusion estimation based on the surface temperature measurement. The method is simpler and more accurate than other methods so it should have many applications in clinical practice. |
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| Keywords: | blood perfusion non invasive estimation constant surface flux heating |
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