亮氨酸类离子液体的合成及其气相色谱分离性能研究

研究亮氨酸类离子液体作为气相色谱固定相的分离性能及其应用.合成了L-亮氨酸乙酯四氟硼酸盐和L-亮氨酸乙酯双（三氟甲基磺酰）亚胺盐离子液体，将其作为固定相制备毛细管气相色谱柱，建立了50，80和110 ℃时的Abraham溶剂化参数模型，选用Grob试剂和正构烷烃混合物对固定相的气相色谱分离能力和选择性进行了考察.结果表明，亮氨酸类离子液体固定相具有良好的涂渍性能，对化合物进行保留所产生的多种相互作用力中，偶极相互作用力和氢键相互作用力占主导地位，具备较好的色谱分离能力和应用价值. 

Synthesis and Application of Leucine-Based Ionic Liquids as Stationary Phases in Gas Chromatography

A study on the leucine-based ionic liquids as stationary phases in gas chromatography was presented.L-Leucine ethyl ester tetrafluoroborate and L-leucine ethyl ester bis (trifluoromethyl) sulfonyl] imide were synthesized and used as stationary phases in gas chromatography.Meanwhile,Abraham solvation parameter models at 50,80 and 110 ℃ were used to evaluate the solvation characteristics.Furthermore,the chromatographic separation performance was evaluated by a Grob test mixture and n-alkanes mixture.The present results demonstrate that the leucine-based ionic liquids stationary phases have good film-forming ability.The system constants indicated that the dipolarity/polarizability and the hydrogen-bond interaction play a major role among five molecular interactions between stationary phases and solute molecules.Leucine-based ionic liquids stationary phases possess excellent chromatographic separation performance,and may be applicable as valuable gas chromatography stationary phases.