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Adenylate cyclase of a human medullary thyroid carcinoma
Authors:S. Matsukura  T. Kakita  M. Fukase  T. Fujita
Affiliation:(1) Third Division, Department of Medicine, Kobe University School of Medicine, Ikuta-ku, 650 Kobe, (Japan);(2) Present address: Endocrine Division, Department of Medicine, Kanazawa Medical College, Uchinada-cho, 920-20 Ishikawa, Japan
Abstract:
Summary The adenylate cyclase of a human medullary thyroid carcinoma was activated by TRH, glucagon, epinephrine, norepinephrine, phentolamine, serotonin and NaF, suggesting the presence of multiple hormone receptors including a beta-adrenergic one in the tumor.Acknowledgment. This work was supported by a grant from the Ministry of Health and Welfare, Japan. We are grateful to Dr H. Imura for invaluable advice.
Keywords:
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