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患包涵体肝炎鸡血淋巴细胞凋亡、坏死的研究
引用本文:王彩云,王纯洁,斯日古楞,贾德刚.患包涵体肝炎鸡血淋巴细胞凋亡、坏死的研究[J].内蒙古大学学报(自然科学版),2005,36(5):546-548.
作者姓名:王彩云  王纯洁  斯日古楞  贾德刚
作者单位:内蒙古农业大学动物科学与医学学院;内蒙古农业大学人事处,呼和浩特,010018;内蒙古农业大学动物科学与医学学院
基金项目:国家自然科学基金资助项目(30160067)
摘    要:运用流式细胞仪技术研究了鸡包涵体肝炎(inclusion body hepatitis,IBH)发病过程中血液淋巴细胞的凋亡、坏死变化情况.结果表明,攻毒组在攻毒后3~5d,淋巴细胞早期凋亡显著下降(P<0.05),7d明显升高(P<0.05),12d时淋巴细胞早期凋亡下降显著(P<0.05).攻毒组在攻毒后3~5d时,淋巴细胞坏死与对照组差异不显著(P>0.05),7~12d时显著低于对照(P<0.05),在25d时显著高于对照组(P<0.05).

关 键 词:IBH  淋巴细胞  凋亡  坏死
文章编号:1000-1638(2005)05-0546-03
收稿时间:2004-12-18
修稿时间:2004年12月18

Apoptosis and Necrosis of Peripheral Blood Lymphocytes of Chickens Infected with IBH Virus
WANG Cai-yun,WANG Chun-jie,Siriguleng,JIA De-gang.Apoptosis and Necrosis of Peripheral Blood Lymphocytes of Chickens Infected with IBH Virus[J].Acta Scientiarum Naturalium Universitatis Neimongol,2005,36(5):546-548.
Authors:WANG Cai-yun  WANG Chun-jie  Siriguleng  JIA De-gang
Abstract:The apoptosis and necrosis of pipheral blood lymphocytes of chicken infected with IBH(inclusion body hepatitis) virus was investigated by using the method of flow cytometer.The result showed that the apoptosis of lymphocytes decreased 3~5 and 12 dpi(days post infection) significantly (P<0.05),whereas increased 7 dpi (P<0.05).But there was no difference between lymphocytes necrosis 3 dpi and 5 dpi, the lymphocytes necrosis 7~12 dpi was lower (P<0.05) and 25 dpi was higher significantly (P<0.05) than that of the contrast.
Keywords:IBH  lymphocyte  apoptosis  necrosis
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