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姜黄素体外抗流感病毒H1N1、H3N2实验研究
引用本文:刘妮,孟以蓉,张俊丽,朱宇同,黄正昌.姜黄素体外抗流感病毒H1N1、H3N2实验研究[J].浙江大学学报(自然科学英文版),2008(9):534-535.
作者姓名:刘妮  孟以蓉  张俊丽  朱宇同  黄正昌
作者单位:广州中医药大学热带医学研究所,广州510405
摘    要:目的:观察姜黄素提取物体外对流感病毒H1N1、H3N2的抑制作用。方法:用狗肾细胞(MDCK)观察姜黄素体外对A型流感病毒H1N1亚型、A型流感病毒H3N2亚型病毒的直接杀灭作用。结果:姜黄素最大无毒浓度为12.5g/L,对H1N1有效抑制浓度为6.25g/L,对H3N2有效抑制浓度为1.56g/L。结论:姜黄素提取物确有明显的抗H1N1、H3N2复制作用。

关 键 词:流感病毒  H1N1  H3N2  姜黄素  抗病毒  实验研究

Effect of Curcumin on Influenza Virus HIN1 and H3N2 in Vitro
Institution:LIU Ni, et al(Guangzhou University of Chinese Medicine, Guangzhou (510405), China)
Abstract:Objective:To investigate the inhibitory effect of curcumin on influenza virus HIN1 and H3N2 in vitro, Methods:The directly killing role of cureumin extract in vitro to influenza virus type A subtype H1N1 and H3N2 was evaluated by the canine kidney cells (MDCK), Results:The largest non toxic concentration of curcumin extract was 12, 5g/L and the effective inhibitory concentration to H1N1 and H3N2 was 6, 25G/1 AND 1,56g/L respectively, Conclusion: Curcumin extract have directly killing effect on H1N1 and H3N2 infections.
Keywords:curcumin  influenza virus  directly killing effect
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