| 结构基因组学研究进展 |
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| 引用本文： | 姜怀春,李宏.结构基因组学研究进展[J].重庆工商大学学报(自然科学版),2012,29(12):76-82. |
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| 作者姓名： | 姜怀春 李宏 |
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| 作者单位： | 1. 重庆工商大学学术期刊社,重庆,400067
2. 重庆第二师范学院生命科学与化学系,重庆,400067 |
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| 摘 要： | 在结构基因组学研究方面,北美洲取得了巨大进展,欧洲是缓慢地开始但是强劲地结束,日本是最先开始进行结构基因组学研究的国家之一,并且一直在努力地从事这方面的研究,澳大利亚也在参与结构基因组学研究。核酸结合蛋白对阐明蛋白质-核酸相互作用机理是非常重要的,用结构基因组学研究蛋白质-核酸作用机理将清楚地解释象癌症、糖尿病等疾病的发病机制,这样人类就可以用相关蛋白质的结构信息合成药物来治疗这些疾病。
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| 关 键 词： | 结构基因组学 核酸-蛋白质相互作用 疾病发病机制 北美洲 欧洲 日本 澳大利亚 |
Research Progress in Structural Genomics |
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| JINAG Huai-chun,LI Hong.Research Progress in Structural Genomics[J].Journal of Chongqing Technology and Business University:Natural Science Edition,2012,29(12):76-82. |
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| Authors: | JINAG Huai-chun LI Hong |
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| Institution: | 1.Academic Periodical Office,Chongqing Technology and Business University,Chongqing 400067,China;2.Department of Life Science and Chemistry,Chongqing Education University,Chongqing 400067,China) |
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| Abstract: | North America has made great progress in structural genomics research,Europe is a slow start but strong finish in structural genomics research,Japan is one of the first countries to initiate strucral genomics and is making efforts to conduct it,and Australia is also participating in structural genomics research.Nucleic acid-bingding proteins are important to calrify the mechanism of nucleic acid-protein interaction for clearly explaining the mechanism of the pathogenesis of some disease by structural genomics research results so that the diseases,such as cancer,diabetes and so on,can be cured by the medicines synthesized according to the information of the related prorein structures. |
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| Keywords: | structural genomics nucleic acid-protein interaction disease mechanism North America Europe Japan Australia |
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