| 小叶女贞叶片提取物药用活性研究 |
| |
| 引用本文： | 倪建成,吕述权,丁骁,谭庆伟.小叶女贞叶片提取物药用活性研究[J].武夷科学,2012,28(1):128-132. |
| |
| 作者姓名： | 倪建成 吕述权 丁骁 谭庆伟 |
| |
| 作者单位： | 1. 福建农林大学生物农药与化学生物学教育部重点实验室,福建福州,350002
2. 福建农林大学植物病毒研究所,福建福州,350002 |
| |
| 基金项目： | 教育部博士点基金（20093515120005）; 福建省自然基金资助项目（2012J01088）; 福建省科技厅重点项目（2009N0016） |
| |
| 摘 要： | 对小叶女贞叶片提取物进行体外抗菌、细胞毒性以及抗氧化药用活性研究,结果表明,小叶女贞叶片提取物对铜绿假单胞菌PAO1具有较强的抑制作用,最小抑制浓度(MIC)为8.0 mg/mL;对人肝癌细胞BEL-7404体外增殖具有显著的抑制作用,浓度在0.6 mg/mL时,抑制率达94.2％；同时具有较强的DPPH自由基清除能力,浓度为15.1 μg/mL时,清除率为85.9％.活性跟踪测试表明,小叶女贞叶片提取物干柱层析得到的各组分中,低极性组分Fr.1为活性部分.
|
| 关 键 词： | 小叶女贞 抑菌 细胞毒 抗氧化 |
Antibacterial,cytotoxic and antioxidant activity of leave extract from Ligustrum quihoui Carr |
| |
| Jian-Cheng NI
,
Shu-Quan LV
,
Xiao DING
,
Qing-Wei TAN.Antibacterial,cytotoxic and antioxidant activity of leave extract from Ligustrum quihoui Carr[J].Wuyi Science Journal,2012,28(1):128-132. |
| |
| Authors: | Jian-Cheng NI Shu-Quan LV Xiao DING Qing-Wei TAN |
| |
| Institution: | 1.Key Laboratory of Biopesticide and Chemical Biology,Ministry of Education,Fujian Agriculture and Forestry University,Fuzhou,Fujian 350002,China;2.Institute of Plant Virology,Fujian Agriculture and Forestry University,Fuzhou,Fujian 350002,China) |
| |
| Abstract: | The aqueous extract of Ligustrum quihoui leaves was tested for antibacterial,cytotoxic and antioxidant activities.The results indicated that the aqueous extract possessed a notable inhibitory effect toward Pseudomonas aeruginosa PAO1 with MIC 8.0 mg/mL.MTT assay showed that the aqueous extract presented significant inhibition on proliferation of human hepatocellular carcinoma cell BEL-7404,with an inhibitory rate of 94.2% at the concentration of 0.6 mg/mL.And the results of antioxidant activity showed that the aqueous extract exhibited strong scavenging capacity,with a DPPH clearance rate of 85.9% at the concentration of 15.1 g/mL. |
| |
| Keywords: | Ligustrum quihoui Carr Antibacterial Cytotoxicity Antioxidant |
| 本文献已被 维普 万方数据 等数据库收录！ |
|
