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金银花饮片和金银花现代饮片RP-HPLC指纹图谱对比研究
引用本文:李文,易进海,刘芳,唐小龙.金银花饮片和金银花现代饮片RP-HPLC指纹图谱对比研究[J].成都大学学报(自然科学版),2012,31(1):21-24.
作者姓名:李文  易进海  刘芳  唐小龙
作者单位:1. 泸州医学院药学院,四川泸州,646000
2. 四川省中医药科学院,四川成都,610041
3. 成都中医药大学药学院,四川成都,610075
摘    要:分别收集10批金银花饮片并制备10批金银花现代饮片,采用RP-HPLC指纹图谱技术,对其进行指纹图谱研究,并建立共有模式,同时,采用"中药色谱指纹图谱相似度评价系统"对所得图谱进行相似度分析.结果表明:金银花饮片和金银花现代饮片所测定的色谱图中,指纹图谱共有峰均有9个,各组分得到很好的分离,相似度评价均大于0.90;金银花饮片和金银花现代饮片指纹图谱之间无明显差异,品质基本一致.

关 键 词:金银花  现代饮片  RP-HPLC  指纹图谱

Comparative Study of RP-HPLC Fingerprints of Traditional Decoction Pieces and Modern Decoction Pieces of Lonicerae Japonicae Flos
LI Wen,YI Jinhai,LIU Fang,TANG Xiaolong.Comparative Study of RP-HPLC Fingerprints of Traditional Decoction Pieces and Modern Decoction Pieces of Lonicerae Japonicae Flos[J].Journal of Chengdu University (Natural Science),2012,31(1):21-24.
Authors:LI Wen  YI Jinhai  LIU Fang  TANG Xiaolong
Institution:(l.School of Pharmacy, Imzhou Medical College, Imhou 646000, China; 2. Sichuan Academy of Chinese Medicine Sciences, Chgdu 610041, China; 3. School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, China)
Abstract:RP-HPLC fingerprint technology was adopted to study the two kinds of fingerprints in which 10 groups of traditional decoction pieces were collected and made into 10 groups of modem ones respectively and to establish a common mode. Similarity evaluation system for chromatographic fingerprint of TCM was utilized to analyze the similarity of the obtained fingerprints. The findings show that there are 9 conmlon peaks which are well separated in the two chromatograms and the similarity is larger than 0.90. It is con- eluded that there is no significant difference between the fingerprints of traditional decoction pieces and modem decoction oieces of Loniceme Jaoonicae Flos, whose qualities are basically equivalent.
Keywords:Lonicerae Japonicae Flos  modem decoction pieces  RP-HPLC  fingerprint
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